| Title: | A two-component signal-transduction cascade in Carnobacterium piscicola LV17B: two signaling peptides and one sensor-transmitter |
| Author(s): | Kleerebezem M; Kuipers OP; de Vos WM; Stiles ME; Quadri LE; |
| Address: | "Wageningen Centre for Food Sciences; NIZO food-research, Department of Flavour and Natural Ingredients, P. O. Box 20, 6710 BA Ede, The Netherlands" |
| DOI: | 10.1016/s0196-9781(01)00494-6 |
| ISSN/ISBN: | 0196-9781 (Print) 0196-9781 (Linking) |
| Abstract: | "In the lactic acid bacterium Carnobacterium piscicola LV17B a peptide-pheromone dependent quorum-sensing mode is involved in the regulation of bacteriocin production. Bacteriocin CB2 was identified as an environmental signal that induces bacteriocin production. Here, we demonstrate that a second 24 amino acid peptide (CS) also induces bacteriocin production. Transcription activation of several carnobacteriocin operons is triggered by CB2 or CS via a two-component signal transduction system composed of CbnK and CbnR" |
| Keywords: | "Bacterial Proteins/*genetics/metabolism Bacteriocins/*biosynthesis/*genetics/metabolism Genes, Regulator/*genetics Lactobacillaceae Operon/genetics Peptides/*genetics/*metabolism Pheromones/genetics/metabolism Plasmids/genetics Promoter Regions, Genetic/d;" |
| Notes: | "MedlineKleerebezem, M Kuipers, O P de Vos, W M Stiles, M E Quadri, L E eng Research Support, Non-U.S. Gov't 2001/10/06 Peptides. 2001 Oct; 22(10):1597-601. doi: 10.1016/s0196-9781(01)00494-6" |
