| Title: | Sol-gel approach for fabrication of coated anodized titanium wire for solid-phase microextraction: highly efficient adsorbents for enrichment of trace polar analytes |
| Author(s): | Jia J; Xu L; Wang S; Wang L; Liu X; |
| Address: | "Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, No. 18 Tianshui Road, Lanzhou, 730000, China" |
| DOI: | 10.1007/s00216-014-7727-6 |
| ISSN/ISBN: | 1618-2650 (Electronic) 1618-2642 (Linking) |
| Abstract: | "Nanotubular titania film was prepared in situ on titanium wire and was used as the fiber substrate for solid-phase microextraction (SPME) because of its high surface-to-volume ratio, easy preparation, and mechanical stability. Three different functional coatings, beta-cyclodextrin (beta-CD), beta-cyclodextrin-co-poly(ethylenepropylene glycol) (beta-CD/PEG), and polyethylene glycol (PEG)-based sorbents were chemically bonded to the nanostructured wire surface via sol-gel technology to further enhance the absorbing capability and extraction selectivity. Coupled to gas chromatography-flame ionic detection (GC-FID), the prepared SPME fibers were investigated using diverse compounds. The results indicated that the fibers showed good mechanical strength, excellent thermal stability, and wonderful capacity and selectivity to polar compounds, including polar aromatic compounds, alcohols, and ketones. Combining the superior hydrophilic property of a bonded functional molecule and the highly porous structure of a fiber coating, the prepared PEG-coated SPME fiber showed much higher adsorption affinity to ephedrine and methylephedrine than beta-CD and beta-CD/PEG fibers. The as-established PEG-coated SPME-GC analytical method provided excellent sensitivity (LODs, 0.004 and 0.001 ng mL(-1) for ephedrine and methylephedrine, respectively) and better linear range (0.01-2 000 mug L(-1)). In addition, it has surprising repeatability and reproducibility. Finally, the present approach was used to analyze ephedrine and methylephedrine from real urine samples, and reliable results were obtained" |
| Keywords: | "Chromatography, Gas Ephedrine/*analogs & derivatives/*urine Flame Ionization Humans Phase Transition Polyethylene Glycols/*chemistry/metabolism Polymethyl Methacrylate/*chemistry/metabolism Solid Phase Microextraction/*methods Titanium/*chemistry/metaboli;" |
| Notes: | "MedlineJia, Jing Xu, Lili Wang, Shuai Wang, Licheng Liu, Xia eng Research Support, Non-U.S. Gov't Germany 2014/04/01 Anal Bioanal Chem. 2014 May; 406(13):3209-17. doi: 10.1007/s00216-014-7727-6. Epub 2014 Mar 30" |
