Title: | A walk-through of the yeast mating pheromone response pathway |
Address: | "Department of Developmental and Cell Biology, 2208 Natural Sciences I, University of California, Irvine, CA 92697-2300, USA. bardwell@uci.edu" |
DOI: | 10.1016/j.peptides.2004.10.002 |
ISSN/ISBN: | 0196-9781 (Print) 1873-5169 (Electronic) 0196-9781 (Linking) |
Abstract: | "The intracellular signal transduction pathway by which the yeast Saccharomyces cerevisiae responds to the presence of peptide mating pheromone in its surroundings is one of the best understood signaling pathways in eukaryotes, yet continues to generate new surprises and insights. In this review, we take a brief walk down the pathway, focusing on how the signal is transmitted from the cell-surface receptor-coupled G protein, via a MAP kinase cascade, to the nucleus" |
Keywords: | "Cell Cycle Cell Membrane/metabolism GTP-Binding Proteins/metabolism MAP Kinase Kinase Kinases/metabolism MAP Kinase Signaling System/physiology Models, Biological Pheromones/*metabolism Receptors, Cell Surface/metabolism Saccharomyces cerevisiae/*metaboli;" |
Notes: | "MedlineBardwell, Lee eng R33 GM069013/GM/NIGMS NIH HHS/ GM60366/GM/NIGMS NIH HHS/ GM69013/GM/NIGMS NIH HHS/ R01 GM060366-05/GM/NIGMS NIH HHS/ R01 GM060366/GM/NIGMS NIH HHS/ R21 GM069013/GM/NIGMS NIH HHS/ Corrected and Republished Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, P.H.S. Review 2005/02/05 Peptides. 2005 Feb; 26(2):339-50. doi: 10.1016/j.peptides.2004.10.002" |