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EMBO J

Title:		How a sex pheromone might act at a concentration below 10(-16) M
Author(s):		Sumper M; Berg E; Wenzl S; Godl K;
Address:		"Lehrstuhl Biochemie I, Universitat Regensburg, Germany"
Journal Title:		EMBO J
Year:		1993
Volume:		12
Issue:		3
Page Number:		831 - 836
DOI:		10.1002/j.1460-2075.1993.tb05723.x
ISSN/ISBN:		0261-4189 (Print) 1460-2075 (Electronic) 0261-4189 (Linking)
Abstract:		"The sex-inducing pheromone of Volvox carteri is a glycoprotein that triggers development of males and females at a concentration below 10(-16) M. Evidence is presented for the existence of a novel mechanism of signal amplification operating within the extracellular matrix of this multicellular organism. A family of 70 kDa matrix glycoproteins denoted pherophorins bear a C-terminal domain being homologous to the sex-inducing pheromone. Under the influence of the pheromone, this domain is liberated by highly specific proteolysis"
Keywords:		Algal Proteins Amino Acid Sequence Animals Base Sequence Chlorophyta DNA Extracellular Matrix Proteins/biosynthesis/genetics/isolation & purification/metabolism/*pharmacology Female Glycoproteins/biosynthesis/genetics/isolation & purification/metabolism/*;
Notes:		"MedlineSumper, M Berg, E Wenzl, S Godl, K eng Research Support, Non-U.S. Gov't England 1993/03/01 EMBO J. 1993 Mar; 12(3):831-6. doi: 10.1002/j.1460-2075.1993.tb05723.x"