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World Allergy Organ J

Title:		Immunopathological features of air pollution and its impact on inflammatory airway diseases (IAD)
Author(s):		Rouadi PW; Idriss SA; Naclerio RM; Peden DB; Ansotegui IJ; Canonica GW; Gonzalez-Diaz SN; Rosario Filho NA; Ivancevich JC; Hellings PW; Murrieta-Aguttes M; Zaitoun FH; Irani C; Karam MR; Bousquet J;
Address:		"Department of Otolaryngology-Head and Neck Surgery, Eye and Ear University Hospital, Beirut, Lebanon. Johns Hopkins University Department of Otolaryngology - Head and Neck Surgery, Baltimore, MD, USA. UNC Center for Environmental Medicine, Asthma, and Lung Biology, Division of Allergy, Immunology and Rheumatology, Department of Pediatrics UNS School of Medicine, USA. Department of Allergy and Immunology, Hospital Quironsalud Bizkaia, Bilbao, Spain. Asthma & Allergy Clinic,Humanitas University & Research Hospital IRCCS, Milano, Italy. University Autonoma de Nuevo Leon Facultad de Medicina y Hospital Universitario U.A.N.L, Monterrey, NL, c.p. 64460, Mexico. Federal University of Parana, Brazil. Faculty of Medicine, Universidad del Salvador, Buenos Aires, Argentina and Head of Allergy and Immunology at the Santa Isabel Clinic, Buenos Aires, Argentina. Department of Otorhinolaryngology, University Hospitals Leuven, Leuven, Belgium. Department of Otorhinolaryngology, Academic Medical Center Amsterdam, The Netherlands - Department Otorhinolaryngology, University Hospital Ghent, Belgium. 8 Rue Pierre Poli, Issy Les Moulineaux, 92130, France. LAUMC Rizk Hospital, Otolaryngology-Allergy Department, Beirut, Lebanon. Department of Internal Medicine and Infectious Diseases, St Joseph University, Hotel Dieu de France Hospital, Beirut, Lebanon. Division of Rheumatology, Allergy and Clinical Immunology, Department of Internal Medicine, American University of Beirut, Beirut, Lebanon. INSERM U 1168, VIMA: Ageing and Chronic Diseases Epidemiological and Public Health Approaches, Villejuif, France. University Versailles St-Quentin-en-Yvelines, France. Allergy-Centre-Charite, Charite-Universitatsmedizin Berlin, Berlin, Germany"
Journal Title:		World Allergy Organ J
Year:		2020
Volume:		20201005
Issue:		10
Page Number:		100467 -
DOI:		10.1016/j.waojou.2020.100467
ISSN/ISBN:		1939-4551 (Print) 1939-4551 (Electronic) 1939-4551 (Linking)
Abstract:		"Air pollution causes significant morbidity and mortality in patients with inflammatory airway diseases (IAD) such as allergic rhinitis (AR), chronic rhinosinusitis (CRS), asthma, and chronic obstructive pulmonary disease (COPD). Oxidative stress in patients with IAD can induce eosinophilic inflammation in the airways, augment atopic allergic sensitization, and increase susceptibility to infection. We reviewed emerging data depicting the involvement of oxidative stress in IAD patients. We evaluated biomarkers, outcome measures and immunopathological alterations across the airway mucosal barrier following exposure, particularly when accentuated by an infectious insult"
Keywords:		"AR, Allergic rhinitis Air pollution Antioxidant COPD, Chronic obstructive pulmonary disease CRS, Chronic rhinosinusitis DEP, Diesel exhaust particles IAD, Inflammatory airway diseases IL, Interleukin ILC, Innate lymphoid cells Inflammatory airway disease;"
Notes:		"PubMed-not-MEDLINERouadi, Philip W Idriss, Samar A Naclerio, Robert M Peden, David B Ansotegui, Ignacio J Canonica, Giorgio Walter Gonzalez-Diaz, Sandra Nora Rosario Filho, Nelson A Ivancevich, Juan Carlos Hellings, Peter W Murrieta-Aguttes, Margarita Zaitoun, Fares H Irani, Carla Karam, Marilyn R Bousquet, Jean eng P30 ES010126/ES/NIEHS NIH HHS/ Review 2020/10/13 World Allergy Organ J. 2020 Oct; 13(10):100467. doi: 10.1016/j.waojou.2020.100467. Epub 2020 Oct 5"