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Curr Genet


Title:"Identification and characterization of brt1, a gene down-regulated during B-regulated development in Schizophyllum commune"
Author(s):Lengeler KB; Kothe E;
Address:"Friedrich-Schiller-Universitat, Biologisch-Pharmazeutische Fakultat, Institut fur Mikrobiologie, Mikrobielle Phytopathologie, Beutenbergstrasse 11, D-07745 Jena, Germany"
Journal Title:Curr Genet
Year:1999
Volume:35
Issue:5
Page Number:551 - 556
DOI: 10.1007/s002940050452
ISSN/ISBN:0172-8083 (Print) 0172-8083 (Linking)
Abstract:"To identify genes regulated by the B mating-type genes a differential RNA display was established for the homobasidiomycete Schizophyllum commune and a gene, brt1, was identified. The mRNA concerned is highly abundant in monokaryotic mycelia and is down-regulated in matings in which either the B genes alone or else both the A and B genes are different between the mates. This places the gene brt1 under the control of the pheromone response system of S. commune encoded by the B mating-type loci. Sequence analysis revealed similarity to a novel protein family, two members of which have been shown to inhibit translational re-initiation"
Keywords:"Base Sequence Blotting, Northern Chromosome Mapping Cloning, Molecular Crosses, Genetic Deoxyribonuclease BamHI/genetics Down-Regulation Fungal Proteins/*genetics/metabolism Gene Deletion *Gene Expression Regulation, Fungal Genetic Markers Genetic Techniq;"
Notes:"MedlineLengeler, K B Kothe, E eng Research Support, Non-U.S. Gov't 1999/06/17 Curr Genet. 1999 Jun; 35(5):551-6. doi: 10.1007/s002940050452"

 
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