| Title: | Drinking water and cancer incidence in Iowa. III. Association of cancer with indices of contamination |
| Author(s): | Isacson P; Bean JA; Splinter R; Olson DB; Kohler J; |
| DOI: | 10.1093/oxfordjournals.aje.a114056 |
| ISSN/ISBN: | 0002-9262 (Print) 0002-9262 (Linking) |
| Abstract: | "With data from the Iowa Cancer Registry, age-adjusted sex-specific cancer incidence rates for the years 1969-1981 were determined for towns with a population of 1,000-10,000 and a public water supply from a single stable ground source. These rates were related to levels of volatile organic compounds and metals found in the finished drinking water of these towns in the spring of 1979. Results showed association between 1,2 dichloroethane and cancers of the colon and rectum and between nickel and cancers of the bladder and lung. The effects were most clearly seen in males. These associations were independent of other water quality and treatment variables and were not explained by occupational or other sociodemographic features including smoking. Because of the low levels of the metals and organics, the authors suggest that they are not causal factors, but rather indicators of possible anthropogenic contamination of other types. The data suggest that water quality variables other than chlorination and trihalomethanes deserve further consideration as to their role in the development of human cancer" |
| Keywords: | "Adolescent Adult Aged Carcinogens, Environmental/*analysis Child Child, Preschool Chlorine Colonic Neoplasms/epidemiology Ethylene Dichlorides/analysis Female Humans Infant Iowa Lung Neoplasms/epidemiology Male Middle Aged Neoplasms/chemically induced/*ep;" |
| Notes: | "MedlineIsacson, P Bean, J A Splinter, R Olson, D B Kohler, J eng N01CP43200/CP/NCI NIH HHS/ Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. 1985/06/01 Am J Epidemiol. 1985 Jun; 121(6):856-69. doi: 10.1093/oxfordjournals.aje.a114056" |
