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Proc Natl Acad Sci U S A

Title:		A central neural circuit for experience-independent olfactory and courtship behavior in Drosophila melanogaster
Author(s):		Heimbeck G; Bugnon V; Gendre N; Keller A; Stocker RF;
Address:		"Department of Biology and Program in Neuroscience, University of Fribourg, CH-1700 Fribourg, Switzerland"
Journal Title:		Proc Natl Acad Sci U S A
Year:		2001
Volume:		20011211
Issue:		26
Page Number:		15336 - 15341
DOI:		10.1073/pnas.011314898
ISSN/ISBN:		0027-8424 (Print) 1091-6490 (Electronic) 0027-8424 (Linking)
Abstract:		"We have studied the function of the major central olfactory pathway in fruit flies. Key elements of this pathway, the projection neurons (PNs), connect the antennal lobes with the lateral protocerebrum both directly and indirectly, the latter via the mushroom bodies (MBs). Transgenic expression of tetanus toxin in the majority of PNs and few MB neurons leads to defects in odor detection and male courtship. Considering behavioral data from flies lacking MBs, our results argue that the direct PN-to-lateral protocerebrum pathway is necessary and sufficient to process these experience-independent behaviors. Moreover, the involvement of an olfactory pathway in male courtship suggests a role of volatile attractive female pheromones in Drosophila"
Keywords:		"Animals Drosophila melanogaster/*physiology Female Genes, Reporter Male Neurons/metabolism/*physiology Odorants *Sexual Behavior, Animal Smell/*physiology Sucrose;"
Notes:		"MedlineHeimbeck, G Bugnon, V Gendre, N Keller, A Stocker, R F eng Research Support, Non-U.S. Gov't 2001/12/14 Proc Natl Acad Sci U S A. 2001 Dec 18; 98(26):15336-41. doi: 10.1073/pnas.011314898. Epub 2001 Dec 11"