| Title: | Breath analysis of cancer in the present and the future |
| Author(s): | Einoch Amor R; Nakhleh MK; Barash O; Haick H; |
| Address: | "Dept of Chemical Engineering and Russell Berrie Nanotechnology Institute, Technion - Israel Institute of Technology, Haifa, Israel. Inserm UMR_S 999, Hopital Marie Lannelongue, Le Plessis-Robinson, France. University of Paris-Sud, Faculte de Medecine, Universite Paris-Saclay, Le Kremlin-Bicetre, France. Dept of Chemical Engineering and Russell Berrie Nanotechnology Institute, Technion - Israel Institute of Technology, Haifa, Israel hhossam@technion.ac.il" |
| DOI: | 10.1183/16000617.0002-2019 |
| ISSN/ISBN: | 1600-0617 (Electronic) 0905-9180 (Print) 0905-9180 (Linking) |
| Abstract: | "Most of the currently used diagnostics for cancerous diseases have yet to meet the standards of screening, as they are insufficiently accurate and/or invasive and risky. In this review, we describe the rationale, the progress made to date, and the potential of analysing the exhaled volatile organic compounds as a pathway for enabling early diagnosis of cancer and, therefore, for achieving better clinical prognosis and survival rates. The review highlights the major advancements made in this field, from fundamentals, up to translational phases and clinical trials, with a special emphasis on sensing platforms based on nanomaterials. The prospects for breath analysis in early cancerous disease are presented and discussed" |
| Keywords: | "Animals Biomarkers, Tumor/*metabolism *Breath Tests Diffusion of Innovation Humans Neoplasms/*diagnosis/metabolism/pathology/therapy Predictive Value of Tests Prognosis Reproducibility of Results Volatile Organic Compounds/*metabolism;" |
| Notes: | "MedlineEinoch Amor, Reef Nakhleh, Morad K Barash, Orna Haick, Hossam eng Review England 2019/06/28 Eur Respir Rev. 2019 Jun 26; 28(152):190002. doi: 10.1183/16000617.0002-2019. Print 2019 Jun 30" |
