| Title: | Volatile sulphur compounds in morning breath of human volunteers |
| Author(s): | Snel J; Burgering M; Smit B; Noordman W; Tangerman A; Winkel EG; Kleerebezem M; |
| Address: | "Health Division, NIZO Food Research, P.O. Box 20, 6710 BA Ede, The Netherlands. Hans.Snel@nizo.nl" |
| DOI: | 10.1016/j.archoralbio.2010.08.016 |
| ISSN/ISBN: | 1879-1506 (Electronic) 0003-9969 (Linking) |
| Abstract: | "OBJECTIVE: morning breath contains elevated concentrations of volatile sulphur components (VSCs). Therefore, morning breath is recognised as a surrogate target for interventions on breath quality. Nevertheless, factors influencing morning breath are poorly understood. Our aim was to evaluate concentrations of VSC at the time of awakening. METHODS: a procedure was developed to collect breath samples at home. Intra- and inter-person variations were determined in two small studies based on measurements of hydrogen sulphide, methyl mercaptan and dimethyl sulphide in healthy volunteers. RESULTS: highest levels of VSC were found directly after waking up, followed by a significant decline afterward. Considerable day-to-day variation was found, but could not be linked to dietary intake. A significantly higher concentration of H(2)S and CH(3)SH was observed in the group of female subjects compared to males. CONCLUSIONS: when morning breath is used as a target for interventions, breath collected at the time of or shortly after waking up is preferred over breath collected later during the morning. Gender plays an important role in VSC levels, and should be taken into account" |
| Keywords: | "Adult Age Factors Alcohol Drinking Chromatography, Gas Coffee Eating Feeding Behavior Female Halitosis/*metabolism Humans Hydrogen Sulfide/analysis Male Middle Aged Sex Factors Smoking Sulfhydryl Compounds/analysis Sulfides/analysis Sulfur Compounds/*anal;" |
| Notes: | "MedlineSnel, Johannes Burgering, Maurits Smit, Bart Noordman, Wouter Tangerman, Albert Winkel, Edwin G Kleerebezem, Michiel eng Comparative Study Research Support, Non-U.S. Gov't England 2010/09/28 Arch Oral Biol. 2011 Jan; 56(1):29-34. doi: 10.1016/j.archoralbio.2010.08.016. Epub 2010 Sep 24" |
