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Science

Title:		Sodefrin: a female-attracting peptide pheromone in newt cloacal glands
Author(s):		Kikuyama S; Toyoda F; Ohmiya Y; Matsuda K; Tanaka S; Hayashi H;
Address:		"Department of Biology, School of Education, Waseda University, Tokyo, Japan"
Journal Title:		Science
Year:		1995
Volume:		267
Issue:		5204
Page Number:		1643 - 1645
DOI:		10.1126/science.7886452
ISSN/ISBN:		0036-8075 (Print) 0036-8075 (Linking)
Abstract:		"A decapeptide called sodefrin was isolated from the abdominal gland of the cloaca of the male red-bellied newt, Cynops pyrrhogaster. The native peptide, as well as the synthetic one, had a female-attracting activity. Sodefrin was found in the apical portion of the epithelial cells of the abdominal gland. Sodefrin is apparently species specific because it did not attract females of Cynops ensicauda. This is the first amphibian pheromone to be identified and the first peptide pheromone identified in a vertebrate"
Keywords:		"Amino Acid Sequence Animals Biological Assay Chromatography, High Pressure Liquid Cloaca/*chemistry Exocrine Glands/*chemistry Female Male Molecular Sequence Data Oligopeptides/analysis/chemistry/*isolation & purification/pharmacology Salamandridae/*metab;"
Notes:		"MedlineKikuyama, S Toyoda, F Ohmiya, Y Matsuda, K Tanaka, S Hayashi, H eng Research Support, Non-U.S. Gov't 1995/03/17 Science. 1995 Mar 17; 267(5204):1643-5. doi: 10.1126/science.7886452"