| Title: | The sensory system: More than just a window to the external world |
| Author(s): | Gendron CM; Chung BY; Pletcher SD; |
| Address: | "Department of Molecular and Integrative Physiology and Geriatrics Center; A. Alfred Taubman Biomedical Sciences and Research Building; University of Michigan ; Ann Arbor, MI USA" |
| DOI: | 10.1080/19420889.2015.1017159 |
| ISSN/ISBN: | 1942-0889 (Print) 1942-0889 (Electronic) 1942-0889 (Linking) |
| Abstract: | "While the traditional importance of the sensory system lies in its ability to perceive external information about the world, emerging discoveries suggest that sensory perception has a greater impact on health and longevity than was previously appreciated. These effects are conserved across species. In this mini-review, we discuss the specific sensory cues that have been identified to significantly impact organismal physiology and lifespan. Ongoing work in the aging field has begun to identify the downstream molecules that mediate the broad effects of sensory signals. Candidates include FOXO, neuropeptide F (NPF), adipokinetic hormone (AKH), dopamine, serotonin, and octopamine. We then discuss the many implications that arise from our current understanding of the effects of sensory perception on health and longevity" |
| Keywords: | Akh Npf aging lifespan model systems pheromones sensory perception; |
| Notes: | "PubMed-not-MEDLINEGendron, Christi M Chung, Brian Y Pletcher, Scott D eng R01 AG030593/AG/NIA NIH HHS/ R37 AG051649/AG/NIA NIH HHS/ 2015/10/21 Commun Integr Biol. 2015 Apr 29; 8(2):e1017159. doi: 10.1080/19420889.2015.1017159. eCollection 2015 Mar-Apr" |
