Title: | Catalytic asymmetric synthesis of enantiopure isoprenoid building blocks: application in the synthesis of apple leafminer pheromones |
Author(s): | van Summeren RP; Reijmer SJ; Feringa BL; Minnaard AJ; |
Address: | "Department of Organic and Molecular Inorganic Chemistry, Stratingh Institute, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands" |
ISSN/ISBN: | 1359-7345 (Print) 1359-7345 (Linking) |
Abstract: | "The first catalytic asymmetric procedure capable of preparing all 4 diastereoisomers (ee > 99%, de > 98%) of a versatile saturated isoprenoid building block was developed and the value of this new method was demonstrated in its application to the concise total synthesis of two pheromones" |
Keywords: | Animals Lepidoptera/*chemistry Molecular Structure Pheromones/*chemical synthesis/*chemistry Stereoisomerism Terpenes/*chemical synthesis/*chemistry; |
Notes: | "Medlinevan Summeren, Ruben P Reijmer, Sven J W Feringa, Ben L Minnaard, Adriaan J eng Research Support, Non-U.S. Gov't England 2005/03/10 Chem Commun (Camb). 2005 Mar 21; (11):1387-9. doi: 10.1039/b419268k. Epub 2005 Feb 9" |