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Oncology


Title:A New Transcutaneous Method for Breast Cancer Detection with Dogs
Author(s):Thuleau A; Gilbert C; Bauer P; Alran S; Fourchotte V; Guillot E; Vincent-Salomon A; Kerihuel JC; Dugay J; Semetey V; Kriegel I; Fromantin I;
Address:"Wound Care Unit, Anesthesia, Intensive Care and Pain Management Department, Institut Curie, Paris, France. Universite Paris-Est, Ecole Nationale Veterinaire d'Alfort, UMR 7179, Laboratoire Mecadev, CNRS/MNHN, Maisons-Alfort, France. Surgery Department, Institut Curie, Paris, France. Pathology and Biology of Tumors Department, Institut Curie, Paris, France. Societe Verticale, Paris, France. Analytical, Bioanalytical and Miniaturization Sciences, UMR PECSA 7195 ESPCI, Paris, France. Chimie ParisTech, PSL Research University, CNRS, Institut de Recherche de Chimie Paris, Paris, France. Wound Care Unit, Anesthesia, Intensive Care and Pain Management Department, Institut Curie, Paris, Franceisabelle.fromantin@curie.fr"
Journal Title:Oncology
Year:2019
Volume:20181002
Issue:2
Page Number:110 - 113
DOI: 10.1159/000492895
ISSN/ISBN:1423-0232 (Electronic) 0030-2414 (Linking)
Abstract:"We developed a new transcutaneous method for breast cancer detection with dogs: 2 dogs were trained to sniff skin secretion samples on compresses that had been worn overnight by women on their breast, and to recognize a breast cancer sample among 4 samples. During the test, the dogs recognized 90.3% of skin secretion breast cancer samples. This proof-of-concept study opens new avenues for the development of a reliable cancer diagnostic tool integrating olfactory abilities of dogs"
Keywords:"Adult Aged Aged, 80 and over Animals Breast Neoplasms/*diagnosis/metabolism Dogs/*physiology Female Humans Middle Aged Skin/metabolism *Smell Volatile Organic Compounds/*analysis/metabolism Breast cancer Detection Dog Sniffer dog;"
Notes:"MedlineThuleau, Aurelie Gilbert, Caroline Bauer, Pierre Alran, Severine Fourchotte, Virginie Guillot, Eugenie Vincent-Salomon, Anne Kerihuel, Jean-Charles Dugay, Jose Semetey, Vincent Kriegel, Irene Fromantin, Isabelle eng Switzerland 2018/10/03 Oncology. 2019; 96(2):110-113. doi: 10.1159/000492895. Epub 2018 Oct 2"

 
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