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Anal Bioanal Chem


Title:Application of ion mobility spectrometry for the detection of human urine
Author(s):Rudnicka J; Mochalski P; Agapiou A; Statheropoulos M; Amann A; Buszewski B;
Address:"Department of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, 7 Gagarin St, 87100 Torun, Poland"
Journal Title:Anal Bioanal Chem
Year:2010
Volume:20100905
Issue:5
Page Number:2031 - 2038
DOI: 10.1007/s00216-010-4147-0
ISSN/ISBN:1618-2650 (Electronic) 1618-2642 (Print) 1618-2642 (Linking)
Abstract:"The aim of the present study was to evaluate the suitability of ion mobility spectrometry (IMS) for the detection of human urine as an indication of human presence during urban search and rescue operations in collapsed buildings. To this end, IMS with a radioactive ionization source and a multicapillary column was used to detect volatile organic compounds (VOCs) emitted from human urine. A study involving a group of 30 healthy volunteers resulted in the selection of seven volatile species, namely acetone, propanal, 3-methyl-2-butanone, 2-methylpropanal, 4-heptanone, 2-heptanone and octanal, which were detected in all samples. Additionally, a preliminary study on the permeation of urine volatiles through the materials surrounding the voids of collapsed buildings was performed. In this study, quartz sand was used as a representative imitating material. Four compounds, namely 3-methyl-2-butanone, octanal, acetone and 2-heptanone, were found to permeate through the sand layers during all experiments. Moreover, their permeation times were the shortest. Although IMS can be considered as a potential technique suitable for the detection, localization and monitoring of VOCs evolved from human urine, further investigation is necessary prior to selecting field chemical methods for the early location of trapped victims"
Keywords:Humans Relief Work Spectrophotometry/*methods Urine/*chemistry Volatile Organic Compounds/*chemistry;
Notes:"MedlineRudnicka, Joanna Mochalski, Pawel Agapiou, Agapios Statheropoulos, Milt Amann, Anton Buszewski, Boguslaw eng Research Support, Non-U.S. Gov't Germany 2010/09/08 Anal Bioanal Chem. 2010 Nov; 398(5):2031-8. doi: 10.1007/s00216-010-4147-0. Epub 2010 Sep 5"

 
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