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Crit Rev Anal Chem

Title:		Evolution and Evaluation of GC Columns
Author(s):		Mametov R; Ratiu IA; Monedeiro F; Ligor T; Buszewski B;
Address:		"Department of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, Torun, Poland. Interdisciplinary Centre for Modern Technologies, Nicolaus Copernicus University, Torun, Poland. Faculty of Chemistry and Chemical Engineering, Babes-Bolyai University, Cluj-Napoca, Romania"
Journal Title:		Crit Rev Anal Chem
Year:		2021
Volume:		20191210
Issue:		2
Page Number:		150 - 173
DOI:		10.1080/10408347.2019.1699013
ISSN/ISBN:		1547-6510 (Electronic) 1040-8347 (Linking)
Abstract:		"A chromatographic column is the fundamental element required for gas-chromatographic analysis. The separation of components coming from complex mixtures, prior to their detection was leading to a prominent revolution in different areas of science. Moreover, current advances in gas chromatographic (GC) columns technology and development have been providing almost unlimited possibilities for analysis employing diverse matrices. We aim through this review article to describe the evolution of chromatographic columns, by pointing the most important stages, as well as the new trends and future perspectives predicted for the new generation of GC columns. Furthermore, it was in our scope to present the main fundamentals regarding the theoretical relationships that describe the chromatographic separation, to introduce concepts related to columns selection in accordance with the required application as well as to discuss the available evaluation parameters for columns efficiency. Consequently, the early stages of first columns preparation up to the development of GC capillary columns used nowadays, together with examples of their applications are also reported and described in detail"
Keywords:		"Biomarkers, Tumor/analysis/metabolism Chromatography, Gas/*methods Humans Neoplasms/diagnosis Polymers/chemistry Porosity Siloxanes/chemistry Volatile Organic Compounds/analysis GC columns characterization GC columns evaluation Mems Mof;"
Notes:		"MedlineMametov, Radik Ratiu, Ileana-Andreea Monedeiro, Fernanda Ligor, Tomasz Buszewski, Boguslaw eng Review 2019/12/11 Crit Rev Anal Chem. 2021; 51(2):150-173. doi: 10.1080/10408347.2019.1699013. Epub 2019 Dec 10"