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Clin Lab

Title:		Is osmol gap an effective screen in accurate prediction of toxic volatiles?
Author(s):		Krahn J; Khajuria A;
Address:		"Department of Pathology and Lab Medicine, College of Medicine, University of Saskatchewan, 103 Hospital Drive, Saskatoon, Canada. john.krahn@usask.ca"
Journal Title:		Clin Lab
Year:		2011
Volume:		57
Issue:		5-Jun
Page Number:		297 - 303
DOI:
ISSN/ISBN:		1433-6510 (Print) 1433-6510 (Linking)
Abstract:		"A review of the literature was done to determine the number of studies published on the osmol gap. We wanted to examine whether these studies were able to establish a consensus on the formula to be used, the appropriate reference interval to be used and finally the performance of the osmol gap in its ability as a screening test for toxic volatile substance. Our study was disappointing since no published literature exists to allow the clinical laboratory to use the osmol gap based on evidenced based studies"
Keywords:		Algorithms Ethanol/blood Ethylene Glycol/blood Humans Methanol/blood Molecular Weight *Osmolar Concentration Quality Control Transition Temperature Volatile Organic Compounds/*blood/pharmacokinetics/toxicity/urine;
Notes:		"MedlineKrahn, John Khajuria, Anna eng Review Germany 2011/07/16 Clin Lab. 2011; 57(5-6):297-303"