« Previous AbstractMating-type genes for basidiomycete strain improvement in mushroom farming    Next AbstractHS-SPME/GC-MS analysis of volatile and semi-volatile organic compounds emitted from municipal sewage sludge »

Curr Genet

Title:		Evolution of multispecific mating-type alleles for pheromone perception in the homobasidiomycete fungi
Author(s):		Kothe E; Gola S; Wendland J;
Address:		"Friedrich-Schiller-Universitat, Department of Microbiology, Microbial Phytopathology, Winzerlaer Strasse 10, 07745 Jena, Germany. Erika.Kothe@uni-jena.de"
Journal Title:		Curr Genet
Year:		2003
Volume:		20021213
Issue:		5
Page Number:		268 - 275
DOI:		10.1007/s00294-002-0352-5
ISSN/ISBN:		0172-8083 (Print) 0172-8083 (Linking)
Abstract:		"The evolution of multiple, independent and multispecific mating-type loci is a feature unique to homobasidiomycete fungi. To propose a model of evolution, data assembled for the wood-rotting fungus Schizophyllum commune were analyzed. In one mating-type locus, pheromone receptors and several pheromones are encoded which have been investigated in some detail and can be used to understand the ligand-receptor interactions and activation of signal transduction which are essential to sexual propagation. Previous models for the evolution of new alleles were complicated and involved three subsequent steps (without selectable phenotype) prior to the establishment of a new stable pheromone-receptor pair. This paper presents a model for the evolution of new specificities by recombination and selection that incorporates the multi-state receptor activation recently established for S. commune, explaining differential responses to different pheromones in one receptor molecule. The model takes into account the occurrence of multiple pheromone genes in each locus and unilateral nuclear donor/acceptor strains that may in nature act as steps in the evolution of new specificities. A second homobasidiomycete fungus, Coprinus cinereus, was similarly characterized at the molecular level. Data acquired in this system support the conclusion that the presented model can be generalized"
Keywords:		"Basidiomycota/*genetics/growth & development/physiology *Biological Evolution Chromosome Mapping Crosses, Genetic Models, Genetic Perception/physiology Pheromones/*physiology Reproduction;"
Notes:		"MedlineKothe, Erika Gola, Susanne Wendland, Jurgen eng Research Support, Non-U.S. Gov't 2003/02/18 Curr Genet. 2003 Feb; 42(5):268-75. doi: 10.1007/s00294-002-0352-5. Epub 2002 Dec 13"