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J Bacteriol

Title:		Alpha mating type-specific expression of mutations leading to constitutive agglutinability in Saccharomyces cerevisiae
Author(s):		Doi S; Yoshimura M;
Address:
Journal Title:		J Bacteriol
Year:		1985
Volume:		161
Issue:		2
Page Number:		596 - 601
DOI:		10.1128/jb.161.2.596-601.1985
ISSN/ISBN:		0021-9193 (Print) 1098-5530 (Electronic) 0021-9193 (Linking)
Abstract:		"Two mutants of Saccharomyces cerevisiae have been isolated and characterized. The mutants were constitutively agglutinable at 36 degrees C, the temperature at which wild-type cells agglutinate only after induction by mating pheromone. The mutant cells had other properties specific for the normal alpha cell type, i.e., conjugation with a cells, response to a mating pheromone, and production of alpha mating pheromone. The two mutations, cag1 and cag2, were recessive and expressed only in alpha cells. cag1 is linked very closely to the MAT locus, but cag2 is unlinked to the MAT locus. These cag mutations complemented ste3-1. These results indicate that CAG genes are novel alpha-specific genes involved in the regulation of sex agglutinin synthesis"
Keywords:		Agglutination Mating Factor *Mutation Peptides/*genetics Phenotype Saccharomyces cerevisiae/*genetics;
Notes:		"MedlineDoi, S Yoshimura, M eng Research Support, Non-U.S. Gov't 1985/02/01 J Bacteriol. 1985 Feb; 161(2):596-601. doi: 10.1128/jb.161.2.596-601.1985"