Title: | Stimulatory effect of volatile urinary components from intact mice on the proliferative activity of splenic lymphoid tissue in irradiated animals |
Author(s): | Tsyb AF; Surinov BP; Yuzhakov VV; Shpagin DV; Bandurko LN; Mihina LN; Fomina NK; |
Address: | "Medical Radiological Research Center, Ministry of Health and Social Development of the Russian Federation, Obninsk, Russia. surinov@mrrc.obninsk.ru" |
DOI: | 10.1007/s10517-013-2227-9 |
ISSN/ISBN: | 1573-8221 (Electronic) 0007-4888 (Linking) |
Abstract: | Immunohistochemical and morphometric analyses have demonstrated long-distance stimulatory effects of the natural volatile components of the urine of intact mice on the proliferation of splenic lymphocytes in mice exposed to a single total gamma-irradiation in a dose of 1 Gy. These results are in line with the data on stimulation of the humoral immune response to thymus-dependent antigen in irradiated mice exposed to urine specimens of intact animals |
Keywords: | Animals;Animals Antibodies/immunology/metabolism Biomarkers/metabolism Cell Proliferation/drug effects/radiation effects Chimera/immunology Erythrocytes/immunology Gamma Rays Immunization Lymphocyte Activation/*drug effects/radiation effects Lymphocytes/cytology/; |
Notes: | "MedlineTsyb, A F Surinov, B P Yuzhakov, V V Shpagin, D V Bandurko, L N Mihina, L N Fomina, N K eng 2013/11/30 Bull Exp Biol Med. 2013 Sep; 155(5):689-91. doi: 10.1007/s10517-013-2227-9" |