| Title: | "Preparation, characterization and pharmaceutical application of linear dextrins. I. Preparation and characterization of amylodextrin, metastable amylodextrins, and metastable amylose" |
| Author(s): | Te Wierik GH; Eissens AC; Besemer AC; Lerk CF; |
| Address: | "Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, The Netherlands" |
| ISSN/ISBN: | 0724-8741 (Print) 0724-8741 (Linking) |
| Abstract: | "The linear dextrin amylodextrin was prepared by enzymatic hydrolysis from waxy maize. Four metastable amylodextrins were prepared by complexation with different volatile organic compounds. All products showed partial dissolution into water at room temperature, because of dissolution of molecules with a lower DP. X-ray diffractometry revealed a helical conformation with six glucose units per turn for amylodextrin and metastable amylodextrins prepared with small molecules, and a helical conformation with seven glucose units per turn for metastable amylodextrins prepared with larger molecules. All metastable amylodextrins showed a helix with reduced distance between two turns as compared to amylodextrin. Metastable amylose, prepared from Amylose V, showed a helical conformation again with a reduced distance between two turns compared to Amylose V. FTIR analysis indicated a more flexible conformation for Amylose V and metastable amylose than for the amylodextrins" |
| Keywords: | "Amylose/*chemistry Dextrins/*chemistry Fourier Analysis Molecular Conformation Polymers Regression Analysis Solubility Spectrophotometry, Infrared X-Ray Diffraction;" |
| Notes: | "MedlineTe Wierik, G H Eissens, A C Besemer, A C Lerk, C F eng 1993/09/01 Pharm Res. 1993 Sep; 10(9):1274-9. doi: 10.1023/a:1018905426751" |
