| Title: | Socio-economic demands and challenges for non-invasive disease diagnosis through a portable breathalyzer by the incorporation of 2D nanosheets and SMO nanocomposites |
| Author(s): | Kalidoss R; Kothalam R; Manikandan A; Jaganathan SK; Khan A; Asiri AM; |
| Address: | "Department of Biomedical Engineering, Bharath Institute of Higher Education and Research Selaiyur Tamil Nadu 600 073 India ramji.sat@gmail.com +91-9840-959832. Department of Chemistry, College of Engineering and Technology, SRM Institute of Science and Technology Kattankulathur Tamil Nadu 603 203 India. Department of Chemistry, Bharath Institute of Higher Education and Research Selaiyur Tamil Nadu 600 073 India. Centre for Nanoscience and Nanotechnology, Bharath Institute of Higher Education and Research Selaiyur Tamil Nadu 600 073 India. Bionanotechnology Research Group, Ton Duc Thang University Ho Chi Minh City Vietnam. Faculty of Applied Sciences, Ton Duc Thang University Ho Chi Minh City Vietnam. Department of Engineering, Faculty of Science and Engineering, University of Hull HU6 7RX UK saravana@tdtu.edu.vn. Chemistry Department, Faculty of Science, King Abdulaziz University Jeddah 21589 Saudi Arabia. Center of Excellence for Advanced Materials Research, King Abdulaziz University Jeddah 21589 Saudi Arabia" |
| ISSN/ISBN: | 2046-2069 (Electronic) 2046-2069 (Linking) |
| Abstract: | "Breath analysis for non-invasive clinical diagnostics and treatment progression has penetrated the research community owing to the technological developments in novel sensing nanomaterials. The trace level selective detection of volatile organic compounds (VOCs) in breath facilitates the study of physiological disorder and real-time health monitoring. This review focuses on advancements in chemiresistive gas sensor technology for biomarker detection associated with different diseases. Emphasis is placed on selective biomarker detection by semiconducting metal oxide (SMO) nanostructures, 2-dimensional nanomaterials (2DMs) and nanocomposites through various optimization strategies and sensing mechanisms. Their synergistic properties for incorporation in a portable breathalyzer have been elucidated. Furthermore, the socio-economic demands of a breathalyzer in terms of recent establishment of startups globally and challenges of a breathalyzer are critically reviewed. This initiative is aimed at highlighting the challenges and scope for improvement to realize a high performance chemiresistive gas sensor for non-invasive disease diagnosis" |
| Notes: | "PubMed-not-MEDLINEKalidoss, Ramji Kothalam, Radhakrishnan Manikandan, A Jaganathan, Saravana Kumar Khan, Anish Asiri, Abdullah M eng Review England 2022/04/29 RSC Adv. 2021 Jun 15; 11(35):21216-21234. doi: 10.1039/d1ra02554f. eCollection 2021 Jun 15" |
