« Previous AbstractVolatile metabolites produced by three strains of Stachybotrys chartarum cultivated on rice and gypsum board    Next Abstract[Pollution Characteristics and Health Risk Assessment of Volatile Organic Compounds in Baiyangdian Lake] »

Am J Clin Exp Urol

Title:		Urinary metabolites for urological cancer detection: a review on the application of volatile organic compounds for cancers
Author(s):		Gao Q; Lee WY;
Address:		"Department of Chemistry and Biochemistry, University of Texas at El Paso El Paso, TX, USA"
Journal Title:		Am J Clin Exp Urol
Year:		2019
Volume:		20190825
Issue:		4
Page Number:		232 - 248
DOI:
ISSN/ISBN:		2330-1910 (Print) 2330-1910 (Electronic) 2330-1910 (Linking)
Abstract:		"Cancer is one of the most devastating human diseases that causes a great number of mortalities each year worldwide. Thus, finding and treating cancers early is of increasing interest to the public and presents great opportunity for research. It is well known that the metabolism of cancer cells differs from that of normal tissues. Analysis of volatile organic compounds (VOCs), a group of small molecule metabolites, provides an emerging approach for cancer screening and disease monitoring. VOCs are continuously generated in human body and released through breath, blood, skin, urine and fecal samples, which carry information of the physiological and metabolic status. Furthermore, the development of effective analytical methods for VOCs detection is one of the challenging aspects in cancer research. In this review, the analytical methods such as solid-phase mirco-extraction (SPME) and stir bar sorptive extraction (SBSE) coupled with gas chromatography/mass spectrometry (GC-MS), the application of VOCs in urological cancers diagnosis and potential molecules pathways related to VOCs profile for cancer detection are discussed"
Keywords:		Urine cancer diagnosis metabolomics volatile organic compounds (VOCs);
Notes:		"PubMed-not-MEDLINEGao, Qin Lee, Wen-Yee eng SC1 CA245675/CA/NCI NIH HHS/ Review 2019/09/13 Am J Clin Exp Urol. 2019 Aug 25; 7(4):232-248. eCollection 2019"