| Title: | "Oxidative damage of the extracts of condensate, particulate and semivolatile organic compounds from gasoline engine exhausts on testicles of rats" |
| Author(s): | Che W; Qiu H; Liu G; Ran Y; Zhang H; Zhang L; Wen W; |
| Address: | "Kunming Center for Disease Control and Prevention, No. 4 Ziyun Road, Kunming, China" |
| Journal Title: | Bull Environ Contam Toxicol |
| DOI: | 10.1007/s00128-009-9757-x |
| ISSN/ISBN: | 1432-0800 (Electronic) 0007-4861 (Linking) |
| Abstract: | "Oxidative damage induced by extracts of condensate, particulate matters and semivolatile organic compounds from gasoline engine exhausts were investigated in testicles of adult Sprague-Dawley rats. The results showed that gasoline engine exhaust could increase the contents of malondialdehyde and carbonyl protein, decrease activities of superoxide dismutase and glutathione peroxidase, and induce DNA damage in testicle of rat. Taking together, the gasoline engine exhaust could promote oxidative damage of bio-macromolecular in testicles of rat and oxidative stress might be an alternative mechanism for male reproductive function of male mammals" |
| Keywords: | "Animals Biomarkers/metabolism DNA Breaks, Single-Stranded/drug effects Gasoline/toxicity Glutathione Peroxidase/metabolism Lipid Peroxidation/drug effects Male Malondialdehyde/metabolism Mutagenicity Tests Oxidative Stress/drug effects Particulate Matter/;" |
| Notes: | "MedlineChe, Wangjun Qiu, Hong Liu, Guiming Ran, Yun Zhang, Hao Zhang, Li Wen, Weihua eng Research Support, Non-U.S. Gov't 2009/05/14 Bull Environ Contam Toxicol. 2009 Jul; 83(1):42-7. doi: 10.1007/s00128-009-9757-x. Epub 2009 May 13" |
