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J Pharm Bioallied Sci


Title:The Relationship between Volatile Sulfur Compounds and the Severity of Chronic Periodontitis: A Cross-sectional Study
Author(s):Abdullah MA; Alasqah M; Sanaa MS; Gufran K;
Address:"Department of Periodontics, Riyadh Elm University, Riyadh, Saudi Arabia. Division of Periodontics, Department of Preventive Dental Sciences, College of Dentistry, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia"
Journal Title:J Pharm Bioallied Sci
Year:2020
Volume:20200828
Issue:Suppl 1
Page Number:S268 - S273
DOI: 10.4103/jpbs.JPBS_81_20
ISSN/ISBN:0976-4879 (Print) 0975-7406 (Electronic) 0975-7406 (Linking)
Abstract:"BACKGROUND: Halitosis is a problem that is often ignored or undervalued. It is not considered a major clinical issue; thus, little is carried out to eradicate it. Little is known about the relationship of malodorous breath with the severity of periodontitis. Hence, the study aimed to investigate the relationship between volatile sulfur compounds (VSCs) and chronic periodontitis. MATERIALS AND METHODS: According to the severity of chronic periodontitis, 80 patients were categorized into four groups (mild, moderate, severe, and control). Probing depth and clinical attachment level were measured. Portable sulfide monitor (Halimeter) is used to assess VSCs. Statistical analyses were conducted using R studio (Northern Ave, Boston). RESULTS: The differences in the VSC levels among the four groups were found to be statistically significant. The greater the severity of periodontitis, the higher the VSC levels found (P < 0.001). Male had higher levels of VSCs than female (225 and 180.53 parts per billion [ppb], respectively). The lowest mean level of VSCs was found in the subjects aged 15-29 years (161.79 ppb); the mean values increased with the age, reaching 282.89 ppb in subjects aged >59 years. CONCLUSION: Highly significant differences were found in the VSC levels among different severities of chronic periodontitis. Moreover, an age-related increase in the VSC levels was determined. In addition, male had higher concentration of VSCs than female"
Keywords:Halitosis periodontitis volatile organic compounds;
Notes:"PubMed-not-MEDLINEAbdullah, M Alrashidi Alasqah, Mohammed Sanaa, M Shafshak Gufran, Khalid eng India 2020/11/06 J Pharm Bioallied Sci. 2020 Aug; 12(Suppl 1):S268-S273. doi: 10.4103/jpbs.JPBS_81_20. Epub 2020 Aug 28"

 
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