« Previous AbstractCharacterization of four endophytic fungi as potential consolidated bioprocessing hosts for conversion of lignocellulose into advanced biofuels    Next AbstractCharacterization and identification of pork flavor compounds and their precursors in Chinese indigenous pig breeds by volatile profiling and multivariate analysis »

J Sep Sci

Title:		Identification of chemical components in Baidianling Capsule based on gas chromatography-mass spectrometry and high-performance liquid chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry
Author(s):		Wu W; Chen Y; Wang B; Sun X; Guo P; Chen X;
Address:		"School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China"
Journal Title:		J Sep Sci
Year:		2017
Volume:		20170721
Issue:		16
Page Number:		3188 - 3195
DOI:		10.1002/jssc.201700033
ISSN/ISBN:		1615-9314 (Electronic) 1615-9306 (Linking)
Abstract:		"Baidianling Capsule, which is made from 16 Chinese herbs, has been widely used for treating vitiligo clinically. In this study, the sensitive and rapid method has been developed for the analysis of chemical components in Baidianling Capsule by gas chromatography-mass spectrometry in combination with retention indices and high-performance liquid chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry. Firstly, a total of 110 potential volatile compounds obtained from different extraction procedures including alkanes, alkenes, alkynes, ketones, ethers, aldehydes, alcohols, phenols, organic acids, esters, furans, pyrrole, acid amides, heterocycles, and oxides were detected from Baidianling Capsule by gas chromatography-mass spectrometry, of which 75 were identified by mass spectrometry in combination with the retention index. Then, a total of 124 components were tentatively identified by high-performance liquid chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry. Fifteen constituents from Baidianling Capsule were accurately identified by comparing the retention times with those of reference compounds, others were identified by comparing the retention times and mass spectrometry data, as well as retrieving the reference literature. This study provides a practical strategy for rapidly screening and identifying the multiple constituents of a complex traditional Chinese medicine"
Keywords:		"*Chromatography, High Pressure Liquid Cyclotrons Drugs, Chinese Herbal/*analysis *Fourier Analysis *Gas Chromatography-Mass Spectrometry Phytochemicals/*analysis Fourier transform ion cyclotron resonance gas chromatographic mass spectrometry traditional C;"
Notes:		"MedlineWu, Wenying Chen, Yu Wang, Binjie Sun, Xiaoyang Guo, Ping Chen, Xiaohui eng Germany 2017/06/21 J Sep Sci. 2017 Aug; 40(16):3188-3195. doi: 10.1002/jssc.201700033. Epub 2017 Jul 21"