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Sensors (Basel)


Title:A bio-inspired two-layer sensing structure of polypeptide and multiple-walled carbon nanotube to sense small molecular gases
Author(s):Wang LC; Su TH; Ho CL; Yang SR; Chiu SW; Kuo HW; Tang KT;
Address:"Analytical Chemistry Section, Chung-Shan Institute of Science & Technology, Hsinchu 30325, Taiwan. rubsico@ms28.hinet.net. Analytical Chemistry Section, Chung-Shan Institute of Science & Technology, Hsinchu 30325, Taiwan. pandasu0926@gmail.com. Analytical Chemistry Section, Chung-Shan Institute of Science & Technology, Hsinchu 30325, Taiwan. johnnie.ho1213@msa.hinet.net. Analytical Chemistry Section, Chung-Shan Institute of Science & Technology, Hsinchu 30325, Taiwan. sunmanup@gmail.com. Department of Electrical Engineering, National Tsing Hua University, No. 101, Sec. 2, Kuang-Fu Road, Hsinchu 30013, Taiwan. swchiu1984@gmail.com. Department of Chemistry, National Central University, Taoyuan 32001, Taiwan. herman.h.kuo@gmail.com. Department of Electrical Engineering, National Tsing Hua University, No. 101, Sec. 2, Kuang-Fu Road, Hsinchu 30013, Taiwan. kttang@ee.nthu.edu.tw"
Journal Title:Sensors (Basel)
Year:2015
Volume:20150305
Issue:3
Page Number:5390 - 5401
DOI: 10.3390/s150305390
ISSN/ISBN:1424-8220 (Electronic) 1424-8220 (Linking)
Abstract:"In this paper, we propose a bio-inspired, two-layer, multiple-walled carbon nanotube (MWCNT)-polypeptide composite sensing device. The MWCNT serves as a responsive and conductive layer, and the nonselective polypeptide (40 mer) coating the top of the MWCNT acts as a filter into which small molecular gases pass. Instead of using selective peptides to sense specific odorants, we propose using nonselective, peptide-based sensors to monitor various types of volatile organic compounds. In this study, depending on gas interaction and molecular sizes, the randomly selected polypeptide enabled the recognition of certain polar volatile chemical vapors, such as amines, and the improved discernment of low-concentration gases. The results of our investigation demonstrated that the polypeptide-coated sensors can detect ammonia at a level of several hundred ppm and barely responded to triethylamine"
Keywords:"Ammonia/chemistry/*isolation & purification Biosensing Techniques/*instrumentation Gases/chemistry/*isolation & purification Nanotubes, Carbon/chemistry Peptides/chemistry Volatile Organic Compounds/chemistry/*isolation & purification;"
Notes:"MedlineWang, Li-Chun Su, Tseng-Hsiung Ho, Cheng-Long Yang, Shang-Ren Chiu, Shih-Wen Kuo, Han-Wen Tang, Kea-Tiong eng Research Support, Non-U.S. Gov't Switzerland 2015/03/10 Sensors (Basel). 2015 Mar 5; 15(3):5390-401. doi: 10.3390/s150305390"

 
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