| Title: | Exposure to Persistent Organic Pollutants Reduces Testosterone Concentrations and Affects Sperm Viability and Morphology during the Mating Peak Period in a Controlled Experiment on Farmed Arctic Foxes (Vulpes lagopus) |
| Author(s): | Sonne C; Torjesen PA; Fuglei E; Muir DCG; Jenssen BM; Jorgensen EH; Dietz R; Ahlstrom O; |
| Address: | "Department of Bioscience, Arctic Research Centre (ARC), Aarhus University, Faculty of Science and Technology , Frederiksborgvej 399, P.O. Box 358, DK-4000 Roskilde, Denmark. Department of Endocrinology, Hormone Laboratory , Oslo University Hospital, NO-0514 Oslo, Norway. Norwegian Polar Institute , Fram Centre, NO-9296 Tromso, Norway. Aquatic Contaminants Research Division, Environment and Climate Change Canada , Burlington, Ontario, Canada L7S 1A1. Department of Biology, Norwegian University of Science and Technology , NO-7491 Trondheim, Norway. Department of Arctic Technology, The University Centre in Svarbard , P.O. Box 156, NO-9171 Longyearbyen, Norway. Department of Arctic and Marine Biology, UiT the Arctic University of Norway , NO-9037 Tromso, Norway. Department of Animal and Aquacultural Sciences, Norwegian University of Life Sciences , NO-1433 As, Norway" |
| ISSN/ISBN: | 1520-5851 (Electronic) 0013-936X (Linking) |
| Abstract: | "We investigated testosterone production and semen parameters in farmed Arctic foxes by dietary exposure to persistent organic pollutants (POPs) for 22 months. Eight male foxes were given a diet of POP-contaminated minke whale blubber, whereas their eight male siblings were fed a control diet containing pig fat as the main fat source. The minke whale-based feed contained a summation operatorPOPs concentration of 802 ng/g ww, whereas the pig-based feed contained summation operatorPOPs of 24 ng/g ww. At the end of the experiment, summation operatorPOP concentrations in adipose tissue were 8856 +/- 2535 ng/g ww in the exposed foxes and 1264 +/- 539 ng/g ww in the control foxes. The exposed group had 45-64% significantly lower testosterone concentrations during their peak mating season compared to the controls (p |
| Keywords: | Animals Arctic Regions Cell Survival/drug effects *Environmental Pollutants Foxes Male Spermatozoa/drug effects/physiology Swine Testosterone/*metabolism; |
| Notes: | "MedlineSonne, Christian Torjesen, Peter A Fuglei, Eva Muir, Derek C G Jenssen, Bjorn Munro Jorgensen, Even H Dietz, Rune Ahlstrom, Oystein eng Research Support, Non-U.S. Gov't 2017/03/17 Environ Sci Technol. 2017 Apr 18; 51(8):4673-4680. doi: 10.1021/acs.est.7b00289. Epub 2017 Mar 30" |
