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Expert Rev Clin Immunol


Title:"Fecal volatile organic compounds: a novel, cheaper method of diagnosing inflammatory bowel disease?"
Author(s):Probert CS; Reade S; Ahmed I;
Address:"Department of Gastroenterology, Institute of Translational Medicine, University of Liverpool, Liverpool, L69 3BX, UK"
Journal Title:Expert Rev Clin Immunol
Year:2014
Volume:20140728
Issue:9
Page Number:1129 - 1131
DOI: 10.1586/1744666X.2014.943664
ISSN/ISBN:1744-8409 (Electronic) 1744-666X (Linking)
Abstract:"The investigation of a novel, cheaper method of diagnosing inflammatory bowel disease (IBD) is an area of active research. Recently, investigations into the metabolomic profile of IBD patients and animal models of colitis compared to healthy controls has begun to receive considerable attention and correlations between the fecal volatile organic compound (VOC) metabolome and IBD is merging. Patients and clinicians have often reported a change in odor of feces during relapse of IBD. Therefore, this article will focus specifically on the fecal VOC metabolome and its potential role in identifying a novel diagnostic method for IBD"
Keywords:"Animals Disease Models, Animal Feces/*chemistry/microbiology Humans Inflammatory Bowel Diseases/*diagnosis/immunology/microbiology Intestinal Mucosa/*metabolism Intestines/immunology/microbiology *Metabolome/immunology Microbiota Odorants/analysis Volatil;"
Notes:"MedlineProbert, Chris S J Reade, Sophie Ahmed, Iftikhar eng Editorial England 2014/07/30 Expert Rev Clin Immunol. 2014 Sep; 10(9):1129-31. doi: 10.1586/1744666X.2014.943664. Epub 2014 Jul 28"

 
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