| Title: | Chemical assessment and in vitro antioxidant capacity of Ficus carica latex |
| Author(s): | Oliveira AP; Silva LR; Ferreres F; Guedes de Pinho P; Valentao P; Silva BM; Pereira JA; Andrade PB; |
| Address: | "REQUIMTE/Department of Pharmacognosy, Faculty of Pharmacy, Porto University, R. Anibal Cunha, Porto, Portugal" |
| ISSN/ISBN: | 1520-5118 (Electronic) 0021-8561 (Linking) |
| Abstract: | "Ficus species possess latex-like material within their vasculatures, affording protection and self-healing from physical attacks. In this work, metabolite profiling was performed on Ficus carica latex. Volatiles profile was determined by HS-SPME/GC-IT-MS, with 34 compounds being identified, distributed by distinct chemical classes: 5 aldehydes, 7 alcohols, 1 ketone, 9 monoterpenes, 9 sesquiterpenes and 3 other compounds. Sesquiterpenes constituted the most abundant class in latex (ca. 91% of total identified compounds). Organic acids composition was also characterized, by HPLC-UV, and oxalic, citric, malic, quinic, shikimic and fumaric acids were determined. Malic and shikimic acids were present in higher amounts (ca. 26%, each). The antioxidant potential of this material was checked by distinct in vitro chemical assays. A concentration-dependent activity was noticed against DPPH, nitric oxide and superoxide radicals. Additionally, acetylcholinesterase inhibitory capacity was evaluated, but a weak effect was found" |
| Keywords: | Antioxidants/*chemistry Ficus/*chemistry Latex/*chemistry Plant Extracts/*chemistry; |
| Notes: | "MedlineOliveira, Andreia P Silva, Luis R Ferreres, Federico Guedes de Pinho, Paula Valentao, Patricia Silva, Branca M Pereira, Jose A Andrade, Paula B eng Research Support, Non-U.S. Gov't 2010/02/18 J Agric Food Chem. 2010 Mar 24; 58(6):3393-8. doi: 10.1021/jf9039759" |
