« Previous AbstractThe neurobiological basis of orientation in insects: insights from the silkmoth mating dance    Next AbstractDescending neurons from the lateral accessory lobe and posterior slope in the brain of the silkmoth Bombyx mori »

Sci Rep

Title:		The morphology of antennal lobe projection neurons is controlled by a POU-domain transcription factor Bmacj6 in the silkmoth Bombyx mori
Author(s):		Namiki S; Fujii T; Shimada T; Kanzaki R;
Address:		"Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro, Tokyo, 153-8904, Japan. namiki@rcast.u-tokyo.ac.jp. Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo, Tokyo, 113-8567, Japan. Laboratory of Silkworm Genetic Resources, Institute of Genetic Resources, Graduate School of Bio Resources and Bioenvironmental Science, Kyushu University, Fukuoka, 812-8581, Japan. Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro, Tokyo, 153-8904, Japan. kanzaki@rcast.u-tokyo.ac.jp"
Journal Title:		Sci Rep
Year:		2017
Volume:		20171025
Issue:		1
Page Number:		14050 -
DOI:		10.1038/s41598-017-14578-4
ISSN/ISBN:		2045-2322 (Electronic) 2045-2322 (Linking)
Abstract:		"How to wire a neural circuit is crucial for the functioning of the nervous system. Here, we describe the neuroanatomy of the olfactory neurons in the spli mutant strain of silkmoth (Bombyx mori) to investigate the function of a transcription factor involved in neuronal wiring in the central olfactory circuit. The genomic structure of the gene Bmacj6, which encodes a class IV POU domain transcription factor, is disrupted in the spli mutant. We report the neuroanatomical abnormality in the morphology of the antennal lobe projection neurons (PNs) that process the sex pheromone. In addition to the mis-targeting of dendrites and axons, we found axonal bifurcation within the PNs. These results indicate that the morphology of neurons in the pheromone processing pathway is modified by Bmacj6"
Keywords:		"Animals Arthropod Antennae/*anatomy & histology/*physiology Axons/chemistry/physiology Bombyx/*physiology Dendrites/chemistry/physiology Gene Expression Regulation Image Processing, Computer-Assisted Insect Proteins/genetics/*metabolism Neurons/chemistry/;"
Notes:		"MedlineNamiki, Shigehiro Fujii, Tsuguru Shimada, Toru Kanzaki, Ryohei eng Research Support, Non-U.S. Gov't England 2017/10/27 Sci Rep. 2017 Oct 25; 7(1):14050. doi: 10.1038/s41598-017-14578-4"