| Title: | Analytical methodology for determination of organic aerosol functional group distributions |
| Author(s): | Kalafut-Pettibone AJ; McGivern WS; |
| Address: | "Chemical Science Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, United States" |
| ISSN/ISBN: | 1520-6882 (Electronic) 0003-2700 (Linking) |
| Abstract: | "Secondary organic aerosol (SOA) particles result from the condensation of oxidized volatile organic compounds (VOC) and consist of a complex mixture that is not conducive to complete compositional analysis. We present a simple methodology for determining the quantities of aldehydes and ketones, alcohols, and carboxylic acids in such samples via derivatization and high-performance liquid chromatography (HPLC) with ultraviolet-visible absorption detection and tandem mass spectrometry (MS/MS). Useful concentration ranges are presented with an examination of the specificity of these compounds in multiply substituted systems. Such data are valuable in modeling the formation of laboratory-generated aerosols and in identifying point sources of field-collected aerosol samples. Calibration curves on standard samples, MS/MS transitions, including collisionally induced dissociation (CID) products, and a quantitative examination of the specificity of the derivatization reagents toward multiple functional groups are presented for a series of aliphatic standard samples. These methods are then applied to filter extracts from SOA derived from 1-iodooctane photolysis at 254 nm to demonstrate the methodology on a complex system. Ultimately, this methodology enables the measurement of variations in the chemical nature of the oxygen within an SOA particle, providing a distribution of functional group concentrations" |
| Notes: | "PubMed-not-MEDLINEKalafut-Pettibone, Alicia J McGivern, W Sean eng 2013/03/07 Anal Chem. 2013 Apr 2; 85(7):3553-60. doi: 10.1021/ac3028728. Epub 2013 Mar 22" |
