| Title: | Chemical composition of essential oils and in vitro antioxidant activity of fresh and dry leaves crude extracts of medicinal plant of Lactuca Sativa L. native to Sultanate of Oman |
| Author(s): | Al Nomaani RS; Hossain MA; Weli AM; Al-Riyami Q; Al-Sabahi JN; |
| Address: | "School of Pharmacy, College of Pharmacy and Nursing, University of Nizwa, P. O. Box 33, Postal Code 616, Nizwa, Sultanate of Oman" |
| DOI: | 10.1016/S2221-1691(13)60076-3 |
| ISSN/ISBN: | 2221-1691 (Print) 2221-1691 (Linking) |
| Abstract: | "OBJECTIVE: To isolate and analyse the chemical composition in the essential oils and free radical scavenging activity of different crude extracts from the fresh and dry leaves of vegetable plants of Lactuca sativa L. (L. sativa). METHODS: The essential oils and volatile chemical constituents were isolated from the fresh and dry leaves of L. sativa (lettuce) grown in Sultanate of Oman by hydro distillation method. The antioxidant activity of the crude extracts was carried out by well established free radical scavenging activity (DPPH) method. RESULTS: About 20 chemical compounds of different concentration representing 83.07% and 79.88% respectively were isolated and identified by gas chromatography-mass spectroscopy in the essential oils isolated from the fresh and dry leaves as alpha-pinene (5.11% and 4.05%), gamma-cymene (2.07% and 1.92%), thymol (11.55% and 10.73%), durenol (52.00% and 49.79%), alpha-terpinene (1.66% and 1.34%), thymol acetate (0.99% and 0.67%), caryophyllene (2.11% and 1.98%), spathulenol (3.09% and 2.98%), camphene (4.11% and 3.65%), limonene (1.28% and 1.11%) representing these major chemical compounds. However, some other minor chemical constituents were also isolated and identified from the essential oil of lettuce including beta-pinene, alpha-terpinolene, linalool, 4-terpineol, alpha-terpineol, o-methylthymol, L-alloaromadendrene and viridiflorene. CONCLUSIONS: The chemical constituents in the essential oils from the locally grown lettuce were identified in the following classes or groups of chemical compounds such as monoterpenes, sesquiterpenes volatile organic compounds and their oxygenated hydrocarbons. Therefore, the essential oils and the crude extracts from Omani vegetable species of lettuce are active candidates which would be used as antioxidant, antifungal or antimicrobial agents in new drugs preparation for therapy of infectious diseases" |
| Keywords: | "Antioxidants/*chemistry/*pharmacology Free Radical Scavengers/chemistry/pharmacology Gas Chromatography-Mass Spectrometry Humans Lettuce/*chemistry Oils, Volatile/*chemistry/*pharmacology Plant Extracts/chemistry/pharmacology Plant Leaves/*chemistry Antio;" |
| Notes: | "MedlineAl Nomaani, Rahma Said Salim Hossain, Mohammad Amzad Weli, Afaf Mohammed Al-Riyami, Qasim Al-Sabahi, Jamal Nasser eng Research Support, Non-U.S. Gov't China 2013/05/07 Asian Pac J Trop Biomed. 2013 May; 3(5):353-7. doi: 10.1016/S2221-1691(13)60076-3" |
