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Chem Biodivers

Title:		"Volatile Profiling, Insecticidal, Antibacterial and Antiproliferative Properties of the Essential Oils of Bursera glabrifolia Leaves"
Author(s):		Villa-Ruano N; Becerra-Martinez E; Cruz-Duran R; Zarate-Reyes JA; Landeta-Cortes G; Romero-Arenas O;
Address:		"Universidad de la Sierra Sur, Guillermo Rojas Mijangos S/N, Ciudad Universitaria, CP 70800, Miahuatlan de Porfirio Diaz Oaxaca, Mexico. Centro de Nanociencias y Micro y Nanotecnologias, Instituto Politecnico Nacional, CP 07738, Ciudad de Mexico. Facultad de Ciencias UNAM, Ciudad Universitaria, Mexico DF, Ciudad Universitaria, CP 04510, Del. Coyoacan, Mexico. Centro Universitario de Vinculacion y Transferencia de Tecnologia, Benemerita Universidad Autonoma de Puebla, CP 72570, Puebla, Mexico. Centro de Agroecologia, Instituto de Ciencias, Benemerita Universidad Autonoma de Puebla, Edificio VAL 1, Km 1,7 carretera a San Baltazar Tetela, San Pedro Zacachimalpa, 72960, Puebla, Mexico"
Journal Title:		Chem Biodivers
Year:		2018
Volume:		20181026
Issue:		11
Page Number:		e1800354 -
DOI:		10.1002/cbdv.201800354
ISSN/ISBN:		1612-1880 (Electronic) 1612-1872 (Linking)
Abstract:		"The present article describes the chemical composition and biological activities of the essential oils of B. glabrifolia leaves obtained in four consecutive years (2015-2018). The essential oils contained alpha-terpineol (17.9-29.7 %), alpha-terpinene (12.6-17.4 %), limonene (14.9-26.8 %) and beta-pinene (2.1-16.7 %) as the most abundant volatiles. The essential oils and these volatiles showed a significant adulticide activity (p<0.01; LC(50) <100 mug mL(-1) ) on the maize weevil (Sitophilus zeamais) with a 100 % mortality rate within a period of 5 h. Also, the essential oils showed a strong antibacterial activity on Enterococcus faecalis ATCC 29212 (MIC, 132.7-173.6 mug mL(-1) ) and Helicobacter pylori ATCC 43504 (MIC, 74.8-199.2 mug mL(-1) ). The assessment of the main volatiles revealed alpha-terpineol as the principal antibacterial agent (MIC, 78.6-149.7 mug mL(-1) ). Similarly, the essential oils exhibited a substantial in vitro antiproliferative activity on the human prostate cancer cell lines PC-3 (LC(50) , 15.2-19.4 mug mL(-1) ), the human ovarian carcinoma cell lines OVCAR-3 (LC(50) , 27.3-53.7 mug mL(-1) ) and the myelogenous leukemia cell lines K-562 (LC(50) , 32.4-75.9 mug mL(-1) ). alpha-Terpineol (LC(50) , 32.4-75.9 mug mL(-1) ) exhibited the strongest antiproliferative effect on these cancer cell lines (LC(50) , 22.4-48.1 mug mL(-1) )"
Keywords:		"Animals Anti-Bacterial Agents/chemistry/isolation & purification/*pharmacology Antineoplastic Agents, Phytogenic/chemistry/isolation & purification/*pharmacology Bursera/*chemistry Cell Line, Tumor Cell Proliferation/drug effects Dose-Response Relationshi;"
Notes:		"MedlineVilla-Ruano, Nemesio Becerra-Martinez, Elvia Cruz-Duran, Ramiro Zarate-Reyes, Jose Alejo Landeta-Cortes, Gerardo Romero-Arenas, Omar eng Sol. 457483/CONACyT-Mexico/ Switzerland 2018/09/07 Chem Biodivers. 2018 Nov; 15(11):e1800354. doi: 10.1002/cbdv.201800354. Epub 2018 Oct 26"