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Chem Biodivers

Title:		Volatile Nitrogenous Compounds from Bacteria: Source of Novel Bioactive Compounds
Author(s):		Valenca CAS; Barbosa AAT; Souto EB; Caramao EB; Jain S;
Address:		"Programa de Pos-Graduacao em Biotecnologia Industrial, Universidade Tiradentes, Aracaju, Sergipe, Brazil. Department of Morphology, Universidade Federal de Sergipe, Sao Cristovao, Sergipe, Brazil. CEB - Center of Biological Engineering, Universidade do Minho, Campus de Gualtar, 4710-057, Braga, Portugal. Instituto Nacional de Ciencia e Tecnologia - Energia e Ambiente, Universidade Federal da Bahia, Salvador, Bahia, Brazil"
Journal Title:		Chem Biodivers
Year:		2021
Volume:		20211013
Issue:		11
Page Number:		e2100549 -
DOI:		10.1002/cbdv.202100549
ISSN/ISBN:		1612-1880 (Electronic) 1612-1872 (Linking)
Abstract:		"Bacteria can produce nitrogenous compounds via both primary and secondary metabolic processes. Many bacterial volatile nitrogenous compounds produced during the secondary metabolism have been identified and reported for their antioxidant, antibacterial, antifungal, algicidal and antitumor activities. The production of these nitrogenous compounds depends on several factors, including the composition of culture media, growth conditions, and even the organic solvent used for their extraction, thus requiring their identification in specific conditions. In this review, we describe the volatile nitrogenous compounds produced by bacteria especially focusing on their antimicrobial activity. We concentrate on azo-compounds mainly pyrazines and pyrrolo-pyridines reported for their activity against several microorganisms. Whenever significant, extraction and identification methods of these compounds are also mentioned and discussed. To the best of our knowledge, this is first review describing volatile nitrogenous compounds from bacteria focusing on their biological activity"
Keywords:		Anti-Bacterial Agents/chemistry/isolation & purification/*pharmacology Azo Compounds/chemistry/isolation & purification/*pharmacology Bacteria/*drug effects Microbial Sensitivity Tests Molecular Structure Volatile Organic Compounds/chemistry/isolation & p;
Notes:		"MedlineValenca, Camilla A S Barbosa, Ana A T Souto, Eliana B Caramao, Elina B Jain, Sona eng UIDB/04469/2020/Portuguese Foundation for Science and Technology/ PT2020/FEDER/ Review Switzerland 2021/10/14 Chem Biodivers. 2021 Nov; 18(11):e2100549. doi: 10.1002/cbdv.202100549. Epub 2021 Oct 13"