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Mol Gen Genet

Title:		Strains of Schizosaccharomyces pombe with a disrupted swi1 gene still show some mating-type switching
Author(s):		Schmidt H;
Address:		"Institut fur Genetik, Technische Universitat Braunschweig, Federal Republic of Germany"
Journal Title:		Mol Gen Genet
Year:		1987
Volume:		210
Issue:		3
Page Number:		485 - 489
DOI:		10.1007/BF00327201
ISSN/ISBN:		0026-8925 (Print) 0026-8925 (Linking)
Abstract:		"The swi1+ gene is necessary for effective mating-type (MT) switching in Schizosaccharomyces pombe. It was cloned on a 4.2 kb genomic DNA fragment. By site-directed integration into the genome and gene disruption experiments it was proved that the swi1+ gene itself and not a suppressor had been isolated. Disruption of the swi1+ gene causes a phenotype identical to that of the original swi1 mutant, i.e. the strain still shows some MT switching. The swi1 gene is unique in the genome and gives rise to a 3 kb mRNA"
Keywords:		"Chromosome Mapping Cloning, Molecular DNA, Fungal/genetics *Genes, Fungal *Genes, Mating Type, Fungal *Genes, Regulator *Genes, Switch Mating Factor Mutation Peptides/genetics Phenotype Saccharomycetales/*genetics Schizosaccharomyces/*genetics;"
Notes:		"MedlineSchmidt, H eng Research Support, Non-U.S. Gov't Germany 1987/12/01 Mol Gen Genet. 1987 Dec; 210(3):485-9. doi: 10.1007/BF00327201"