| Title: | Higher health risk resulted from dermal exposure to PCBs than HFRs and the influence of haze |
| Author(s): | Cao Z; Chen Q; Ren M; Zhang L; Shen F; Wang X; Shi S; Zhao Y; Yan G; Peng J; |
| Address: | "School of Environment, Key Laboratory for Yellow River and Huai River Water Environment and Pollution Control, Ministry of Education, Henan Normal University, Xinxiang 453007, China; Beijing Key Laboratory for Emerging Organic Contaminants Control, Tsinghua University, Beijing 100084, China. Electronic address: wq11ab@163.com. School of Environment, Key Laboratory for Yellow River and Huai River Water Environment and Pollution Control, Ministry of Education, Henan Normal University, Xinxiang 453007, China" |
| DOI: | 10.1016/j.scitotenv.2019.06.429 |
| ISSN/ISBN: | 1879-1026 (Electronic) 0048-9697 (Linking) |
| Abstract: | "To investigate the influence of haze on human dermal exposure to a series of halogenated flame retardants (HFRs) and polychlorinated biphenyls (PCBs), paired forehead wipes were collected from 46 volunteers (23 males, 23 females) using gauze pads soaked in isopropyl alcohol under heavy and light haze pollution levels. The median levels of summation operator(27)HFRs and summation operator(27)PCBs in all 92 samples were 672 and 1300ng/m(2), respectively. Decabromodiphenyl ether (BDE-209) (171ng/m(2)) and decabromodiphenylethane (DBDPE) (134ng/m(2)) were the dominant components of HFRs, indicating that dermal exposure may also be the significant pathway for non-volatile compounds. PCB-37 contributed the most to summation operator(27)PCBs, with a median concentration of 194ng/m(2), followed by PCB-60 (141ng/m(2)). Generally, PBDE, PCB and DD (dehalogenated derivatives of DPs) levels on the foreheads of female participants (291, 1340, 0.92ng/m(2)) were higher (p=0.037, 0.001, and 0.031, respectively) than those of male participants (226, 989, and 0.45ng/m(2)). A significant difference (p=0.001) in PCBs was found between light (1690ng/m(2)) and heavy (996ng/m(2)) haze pollution conditions. Nevertheless, HFR levels under heavy (median=595ng/m(2), ranging from 295 to 1490ng/m(2)) and light haze pollution conditions (ranging from 205 to 1220ng/m(2) with a median of 689ng/m(2)) did not show significant differences (p=0.269). The non-carcinogenic health risk resulting from dermal exposure to summation operator(8)HFRs and summation operator(27)PCBs was 8.72x10(-5) and 1.63x10(-2), respectively, raising more concern about populations' exposure to PCBs than HFRs" |
| Keywords: | Air Pollution/*analysis *Environmental Exposure Environmental Monitoring Environmental Pollutants/*adverse effects Female Flame Retardants/*adverse effects Halogenation Humans Male Polychlorinated Biphenyls/*adverse effects Risk Assessment Skin Dermal exp; |
| Notes: | "MedlineCao, Zhiguo Chen, Qiaoying Ren, Meihui Zhang, Ling Shen, Fangfang Wang, Xiaoying Shi, Shiyu Zhao, Youhua Yan, Guangxuan Peng, Jianbiao eng Netherlands 2019/07/05 Sci Total Environ. 2019 Nov 1; 689:223-231. doi: 10.1016/j.scitotenv.2019.06.429. Epub 2019 Jun 26" |
