| Title: | Weapons against Themselves: Identification and Use of Quorum Sensing Volatile Molecules to Control Plant Pathogenic Fungi Growth |
| Author(s): | De Clerck C; Josselin L; Vangoethem V; Lassois L; Fauconnier ML; Jijakli H; |
| Address: | "AgricultureIsLife, Gembloux Agro-Bio Tech, Liege University, Passage des Deportes 2, 5030 Gembloux, Belgium. Laboratory of Chemistry of Natural Molecules, Gembloux Agro-Bio Tech, Liege University, Passage des Deportes 2, 5030 Gembloux, Belgium. Integrated and Urban Plant Pathology Laboratory, Gembloux Agro-Bio Tech, Liege University, Passage des Deportes 2, 5030 Gembloux, Belgium. Plant Genetics and Rhizosphere Processes Lab., Gembloux Agro-Bio Tech, Liege University, Passage des Deportes 2, 5030 Gembloux, Belgium" |
| DOI: | 10.3390/microorganisms10122459 |
| ISSN/ISBN: | 2076-2607 (Print) 2076-2607 (Electronic) 2076-2607 (Linking) |
| Abstract: | "Quorum sensing (QS) is often defined as a mechanism of microbial communication that can regulate microbial behaviors in accordance with population density. Much is known about QS mechanisms in bacteria, but fungal QS research is still in its infancy. In this study, the molecules constituting the volatolomes of the plant pathogenic fungi Fusarium culmorum and Cochliobolus sativus have been identified during culture conditions involving low and high spore concentrations, with the high concentration imitating overpopulation conditions (for QS stimulation). We determined that volatolomes emitted by these species in conditions of overpopulation have a negative impact on their mycelial growth, with some of the emitted molecules possibly acting as QSM. Candidate VOCs related to QS have then been identified by testing the effect of individual volatile organic compounds (VOCs) on mycelial growth of their emitting species. The antifungal effect observed for the volatolome of F. culmorum in the overpopulation condition could be attributed to ethyl acetate, 2-methylpropan-1-ol, 3-methylbutyl ethanoate, 3-methylbutan-1-ol, and pentan-1-ol, while it could be attributed to longifolene, 3-methylbutan-1-ol, 2-methylpropan-1-ol, and ethyl acetate for C. sativus in the overpopulation condition. This work could pave the way to a sustainable alternative to chemical fungicides" |
| Keywords: | Cochliobolus sativus Fusarium culmorum antifungal quorum sensing volatile organic compounds (VOCs); |
| Notes: | "PubMed-not-MEDLINEDe Clerck, Caroline Josselin, Laurie Vangoethem, Valentine Lassois, Ludivine Fauconnier, Marie-Laure Jijakli, Haissam eng T105515F/Fund for Scientific Research/ Switzerland 2022/12/24 Microorganisms. 2022 Dec 13; 10(12):2459. doi: 10.3390/microorganisms10122459" |
