| Title: | "Aphrodisin, an aphrodisiac lipocalin secreted in hamster vaginal secretions" |
| Author(s): | Briand L; Trotier D; Pernollet JC; |
| Address: | "Biochimie et Structure des Proteines, INRA, UR 477, F-78352 Jouy-en-Josas, France" |
| DOI: | 10.1016/j.peptides.2003.10.026 |
| ISSN/ISBN: | 0196-9781 (Print) 0196-9781 (Linking) |
| Abstract: | "Vertebrates communicate through pheromones, which favor biological regulations within each species. Aphrodisin, a protein belonging to the lipocalin superfamily, found in hamster vaginal secretions, is detected by the male accessory olfactory system and induces or facilitates its copulatory behavior. Although much is known about aphrodisin structure, the question of whether aphrodisin bears itself the pheromonal function or is simply a carrier for hydrophobic small pheromones has not been definitely solved. Arguments based on use of recombinant aphrodisin deprived of any natural ligand and its capability to convey hamster pheromonal compounds will be discussed, together with progresses concerning putative natural ligand(s)" |
| Keywords: | "Amino Acid Sequence Animals Carrier Proteins/*chemistry Cricetinae Female Gene Expression Regulation Ligands Lipocalin 1 Male Models, Molecular Molecular Sequence Data Olfactory Pathways/physiology Pheromones/chemistry/metabolism Protein Conformation Prot;" |
| Notes: | "MedlineBriand, Loic Trotier, Didier Pernollet, Jean-Claude eng Review 2004/09/18 Peptides. 2004 Sep; 25(9):1545-52. doi: 10.1016/j.peptides.2003.10.026" |
