| Title: | Antifungal activity of zedoary turmeric oil against Phytophthora capsici through damaging cell membrane |
| Author(s): | Wang B; Liu F; Li Q; Xu S; Zhao X; Xue P; Feng X; |
| Address: | "Jiangsu Key Laboratory for the Research and Utilization of Plant Resources, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing 210014, China; The Jiangsu Provincial Platform for Conservation and Utilization of Agricultural Germplasm, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing 210014, China. College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China. Jiangsu Key Laboratory for the Research and Utilization of Plant Resources, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing 210014, China; The Jiangsu Provincial Platform for Conservation and Utilization of Agricultural Germplasm, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing 210014, China. Electronic address: fengxucnbg@cnbg.net" |
| DOI: | 10.1016/j.pestbp.2019.05.014 |
| ISSN/ISBN: | 1095-9939 (Electronic) 0048-3575 (Linking) |
| Abstract: | "Phytophthora capsici is a plant oomycete pathogen, which causes many devastating diseases on a broad range of hosts. Zedoary turmeric oil (ZTO) is a kind of natural plant essential oil that has been widely used in pharmaceutical applications. However, the antifungal activity of ZTO against phytopathogens remains unknown. In this study, we found ZTO could inhibit P. capsici growth and development in vitro and in detached cucumber and Nicotiana benthamiana leaves. Besides, ZTO treatment resulted in severe damage to the cell membrane of P. capsici, leading to the leakage of intracellular contents. ZTO also induced a significant increase in relative conductivity, malondialdehyde concentration and glycerol content. Furthermore, we identified 50 volatile organic compounds from ZTO, and uncovered Curcumol, beta-elemene, curdione and curcumenol with strong inhibitory activities against mycelial growth of P. capsici. Overall, our results not only shed new light on the antifungal mechanism of ZTO, but also imply a promising alternative for the control of phytophthora blight caused by P. capsici" |
| Keywords: | "Antifungal Agents/*pharmacology Cell Membrane/*drug effects Curcuma Oils, Volatile/*pharmacology Phytophthora/*drug effects/metabolism Plant Extracts/*pharmacology Plant Oils/*pharmacology Sesquiterpenes/pharmacology Sesquiterpenes, Germacrane/pharmacolog;" |
| Notes: | "MedlineWang, Bi Liu, Fei Li, Qi Xu, Shu Zhao, Xingzeng Xue, Peilin Feng, Xu eng 2019/08/12 Pestic Biochem Physiol. 2019 Sep; 159:59-67. doi: 10.1016/j.pestbp.2019.05.014. Epub 2019 May 24" |
