| Title: | "Concomitant exposure to area-level poverty, ambient air volatile organic compounds, and cardiometabolic dysfunction: a cross-sectional study of U.S. adolescents" |
| Author(s): | Shenassa ED; Williams AD; |
| Address: | "Maternal and Child Health Program, Department of Family Science, University of Maryland, College Park; Department of Epidemiology and Biostatistics, University of Maryland, College Park, MD; Department of Epidemiology and Biostatistics, School of Public Health, Brown University, Providence, RI; Department of Epidemiology and Biostatistics, School of Medicine, University of Maryland Baltimore, Baltimore, MD. Electronic address: shenassa@umd.edu. Public Health Program, School of Medicine & Health Sciences, University of North Dakota, Grand Forks" |
| DOI: | 10.1016/j.annepidem.2020.05.014 |
| ISSN/ISBN: | 1873-2585 (Electronic) 1047-2797 (Linking) |
| Abstract: | "PURPOSE: A key to better understanding the influence of the place of residence on cardiometabolic function is the effect of concomitant exposure to both air pollution and residence in economically marginalized areas. We hypothesized that, among adolescents, the association between air pollution and cardiometabolic function is exacerbated among residents of economically marginalized areas. METHODS: In this cross-sectional study, individual-level data on cardiometabolic function collected from a representative sample of U.S. adolescents in the National Health and Nutrition Examination Survey (n = 10,415) were merged with data on area-level poverty (U.S. decennial survey and American Community Survey) and air pollution levels (National-Scale Air Toxics Assessment ) using contemporary census-tract identifiers. We excluded respondents who were pregnant, had hypertension or diabetes or using medication for hypertension or diabetes, or with missing data on outcome variables. RESULTS: We observed a significant interaction between area-level poverty and air pollution. Among residents of high-poverty areas, exposure to high levels of air pollution predicted a 30% elevated odds of cardiometabolic dysfunction (OR = 1.30; 95% CI: 1.04, 1.61), whereas in low-poverty areas, exposure to high levels of air pollution was not associated with elevated odds of cardiometabolic dysfunction (OR = 1.04; 95% CI: 0.85, 1.28). CONCLUSIONS: Our findings suggest that the cardiometabolic consequences of air pollution are more readily realized among residents of economically marginalized areas. Structural remedies are discussed" |
| Keywords: | Adolescent Air Pollutants/*adverse effects/analysis Air Pollution/*adverse effects Cardiovascular Diseases/*epidemiology/etiology Cross-Sectional Studies Environmental Exposure/*adverse effects Female Humans Male Nutrition Surveys Particulate Matter/analy; |
| Notes: | "MedlineShenassa, Edmond D Williams, Andrew D eng Research Support, Non-U.S. Gov't 2020/08/12 Ann Epidemiol. 2020 Aug; 48:15-22. doi: 10.1016/j.annepidem.2020.05.014. Epub 2020 Jun 5" |
