| Title: | The anatomy and functional role of the circumvallate papilla/von Ebner gland complex |
| Author(s): | Sbarbati A; Crescimanno C; Osculati F; |
| Address: | "Institute of Human Anatomy and Histology, University of Verona, Italy" |
| ISSN/ISBN: | 0306-9877 (Print) 0306-9877 (Linking) |
| Abstract: | "We suggest that the description of the reciprocal relationships between the circumvallate papilla (CP) and von Ebner glands (VEGs) reported in most textbooks of anatomy must be rewritten. In the past, the VEG was described as a gland ancillary to the taste buds, mainly involved in the washing of the vallum around the CP or in perireceptorial events. Recent data obtained in our laboratory or reported in the literature indicate that both these structures form a single functional unity which could be called circumvallata papilla/von Ebner gland (CP/VEG) complex. The CP/VEG complex seems to represent an important enzyme- and pheromone-producing system composed of a sensitive (taste buds) and an effectory (VEG) branch linked by feedback mechanisms of control. In our hypothesis, the taste buds located in the distal portion of the VEG ductal system can be considered similar to the chemoreceptory cells located in other portions of the digestive apparatus such as pancreatic and bile ducts. Therefore, the CP/VEG complex represents a rare example of chemoreceptor-secretory organ" |
| Keywords: | "Humans *Models, Biological Taste Buds/*anatomy & histology/physiology;" |
| Notes: | "MedlineSbarbati, A Crescimanno, C Osculati, F eng 1999/09/28 Med Hypotheses. 1999 Jul; 53(1):40-4. doi: 10.1054/mehy.1997.0708" |
