| Title: | Coupling calcium/calmodulin-mediated signaling and herbivore-induced plant response through calmodulin-binding transcription factor AtSR1/CAMTA3 |
| Author(s): | Qiu Y; Xi J; Du L; Suttle JC; Poovaiah BW; |
| Address: | "Molecular Plant Science, Department of Horticulture, Washington State University, Pullman, WA 99164-6414, USA" |
| DOI: | 10.1007/s11103-012-9896-z |
| ISSN/ISBN: | 1573-5028 (Electronic) 0167-4412 (Linking) |
| Abstract: | "Calcium/calmodulin (Ca(2+)/CaM) has long been considered a crucial component in wound signaling pathway. However, very few Ca(2+)/CaM-binding proteins have been identified which regulate plant responses to herbivore attack/wounding stress. We have reported earlier that a family of Ca(2+)/CaM-binding transcription factors designated as AtSRs (also known as AtCAMTAs) can respond differentially to wounding stress. Further studies revealed that AtSR1/CAMTA3 is a negative regulator of plant defense, and Ca(2+)/CaM-binding to AtSR1 is indispensable for the suppression of salicylic acid (SA) accumulation and disease resistance. Here we report that Ca(2+)/CaM-binding is also critical for AtSR1-mediated herbivore-induced wound response. Interestingly, atsr1 mutant plants are more susceptible to herbivore attack than wild-type plants. Complementation of atsr1 mutant plants by overexpressing wild-type AtSR1 protein can effectively restore plant resistance to herbivore attack. However, when mutants of AtSR1 with impaired CaM-binding ability were overexpressed in atsr1 mutant plants, plant resistance to herbivore attack was not restored, suggesting a key role for Ca(2+)/CaM-binding in wound signaling. Furthermore, it was observed that elevated SA levels in atsr1 mutant plants have a negative impact on both basal and induced biosynthesis of jasmonates (JA). These results revealed that Ca(2+)/CaM-mediated signaling regulates plant response to herbivore attack/wounding by modulating the SA-JA crosstalk through AtSR1" |
| Keywords: | Animals Arabidopsis/drug effects/*immunology/*parasitology Arabidopsis Proteins/*metabolism *Calcium Signaling/drug effects Calmodulin/*metabolism Cyclopentanes/pharmacology Herbivory/drug effects/*physiology Insecta/drug effects/physiology Larva/drug eff; |
| Notes: | "MedlineQiu, Yongjian Xi, Jing Du, Liqun Suttle, Jeffrey C Poovaiah, B W eng Research Support, U.S. Gov't, Non-P.H.S. Netherlands 2012/03/01 Plant Mol Biol. 2012 May; 79(1-2):89-99. doi: 10.1007/s11103-012-9896-z. Epub 2012 Feb 28" |
