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Pediatr Allergy Immunol

Title:		Atopic dermatitis severity during exposure to air pollutants and weather changes with an Artificial Neural Network (ANN) analysis
Author(s):		Patella V; Florio G; Palmieri M; Bousquet J; Tonacci A; Giuliano A; Gangemi S;
Address:		"Division Allergy and Clinical Immunology, Department of Medicine ASL Salerno, 'Santa Maria della Speranza' Hospital, Salerno, Italy. Postgraduate Program in Allergy and Clinical Immunology, University of Naples Federico II, Naples, Italy. Former Primary of Unit of Pediatry, Hospital of Eboli, Salerno, Italy. MACVIA-France and University Hospital, Montpellier, France. Charite - Universitatsmedizin Berlin, Humboldt-Universitat zu Berlin, Berlin, Germany. Department of Dermatology and Allergy, Berlin Institute of Health, Comprehensive Allergy Center, Berlin, Germany. Institute of Clinical Physiology-National Research Council of Italy (IFC-CNR), Pisa, Italy. Laboratory of Toxicology Analysis, Department for the Treatment of Addictions, ASL Salerno, Salerno, Italy. School and Unit of Allergy and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy"
Journal Title:		Pediatr Allergy Immunol
Year:		2020
Volume:		20200820
Issue:		8
Page Number:		938 - 945
DOI:		10.1111/pai.13314
ISSN/ISBN:		1399-3038 (Electronic) 0905-6157 (Linking)
Abstract:		"BACKGROUND: Epidemiological studies have shown an association between global warming, air pollution, and allergic diseases. Several air pollutants, including volatile organic compounds, formaldehyde, toluene, nitrogen dioxide (NO(2) ), and particulate matter, act as risk factors for the development or aggravation of atopic dermatitis (AD). We evaluated the impact of air pollutants and weather changes on AD patients. MATERIALS AND METHODS: Sixty AD patients >/=5 years of age (mean age: 23.5 +/- 12.5 years), living in the Campania Region (Southern Italy), were followed for 18 months. The primary outcome was the effect of atmospheric and climatic factors on signs and symptoms of AD, assessed using the SCORAD (SCORing Atopic Dermatitis) index. We measured mean daily temperature (TOD), outdoor relative humidity (RH), diurnal temperature range (DTR), precipitation, particulate with aerodynamic diameter
Keywords:		"Adult *Air Pollutants/adverse effects/analysis *Air Pollution/adverse effects *Dermatitis, Atopic/epidemiology Humans Infant, Newborn Neural Networks, Computer Nitrogen Dioxide/analysis *Ozone/analysis Particulate Matter/adverse effects Weather Young Adul;"
Notes:		"MedlinePatella, Vincenzo Florio, Giovanni Palmieri, Mario Bousquet, Jean Tonacci, Alessandro Giuliano, Ada Gangemi, Sebastiano eng England 2020/06/26 Pediatr Allergy Immunol. 2020 Nov; 31(8):938-945. doi: 10.1111/pai.13314. Epub 2020 Aug 20"