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Clin Chim Acta

Title:		(2-Ethoxyethoxy)acetic acid: an unusual compound found in the gas chromatographic analysis of urinary organic acids
Author(s):		Kamerling JP; Duran M; Bruinvis L; Ketting D; Wadman SK; de Groot CJ; Hommes FA;
Address:
Journal Title:		Clin Chim Acta
Year:		1977
Volume:		77
Issue:		3
Page Number:		397 - 405
DOI:		10.1016/0009-8981(77)90246-7
ISSN/ISBN:		0009-8981 (Print) 0009-8981 (Linking)
Abstract:		"An unknown acidic compound was detected in a number of urine samples from patients with a suspected metabolic disorder and some patients treated with chemotherapy. The structure of this compound has been characterized as (2-ethoxyethoxy)acetic acid, using a gas chromatography/mass spectrometry/computer system. The authentic compound was synthesized and compared with the unknown. Urinary (2-ethoxyethoxy)acetic acid is assumed to be formed endogenously from an exogenous precursor, probably 2-(2-ethoxyethoxy)ethanol"
Keywords:		"Acetates/chemical synthesis/*urine Child Child, Preschool Chromatography, Gas Ethyl Ethers/*urine Ethylene Glycols Female Humans Infant Mass Spectrometry Volatilization;"
Notes:		"MedlineKamerling, J P Duran, M Bruinvis, L Ketting, D Wadman, S K de Groot, C J Hommes, F A eng Case Reports Netherlands 1977/06/15 Clin Chim Acta. 1977 Jun 15; 77(3):397-405. doi: 10.1016/0009-8981(77)90246-7"