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Org Biomol Chem

Title:		"Sequential oxonium-olefin-alkyne cyclization for the stereoselective synthesis of (octahydro-1H-pyrano[3,4-c]pyridin-5-yl)methanone derivatives"
Author(s):		Subba Reddy BV; Hanuman Reddy V; Durgaprasad M; Gopal Reddy S; Lakshmi JK; Aneesh PV; Rami Reddy YV;
Address:		"Centre for Semiochemicals, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India. Centre for Semiochemicals, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India and Department of Chemistry, S. V. University, Tirupati 517502, India. basireddy@iict.res.in. Centre for Nuclear Magnetic Resonance, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India. Department of Chemistry, S. V. University, Tirupati 517502, India. basireddy@iict.res.in"
Journal Title:		Org Biomol Chem
Year:		2016
Volume:		14
Issue:		48
Page Number:		11396 - 11401
DOI:		10.1039/c6ob01641c
ISSN/ISBN:		1477-0539 (Electronic) 1477-0520 (Linking)
Abstract:		"A broad range of aldehydes undergo a smooth cascade cyclization with (E)-5-(3-phenylprop-2-ynylamino)pent-3-en-1-ol in the presence of BF(3).OEt(2) at room temperature to furnish a novel series of (octahydro-1H-pyrano[3,4-c]pyridin-5-yl)methanone derivatives in good yields and diastereoselectivities. This cascade process provides a simple and proficient alternative for the stereoselective construction of fused pyranopiperidine derivatives"
Keywords:
Notes:		"PubMed-not-MEDLINESubba Reddy, B V Hanuman Reddy, V Durgaprasad, M Gopal Reddy, S Lakshmi, J K Aneesh, P V Rami Reddy, Y V eng England 2016/11/20 Org Biomol Chem. 2016 Dec 7; 14(48):11396-11401. doi: 10.1039/c6ob01641c"