| Title: | Unconventional approaches for the introduction of sulfur-based functional groups |
| Author(s): | Lanfranco A; Moro R; Azzi E; Deagostino A; Renzi P; |
| Address: | "Department of Chemistry, University of Torino, Via Giuria, 7, Torino, 10125, Italy. polyssena.renzi@unito.it" |
| ISSN/ISBN: | 1477-0539 (Electronic) 1477-0520 (Linking) |
| Abstract: | "Organosulfur compounds have a pivotal role in the functionalities of many natural products, pharmaceuticals and organic materials. For these reasons, the search for new methodologies for the formation of carbon-sulfur bonds has been the object of intensive work for organic chemists. However, the proposed strategies suffer from various drawbacks, such as volatility, toxicity, and instability of the sulfur sources or the use of VOC solvents. In this review, we summarise the recent protocols which have the goal of obtaining sulfones, thioethers, thiazines, thiazepines and sulfonamides in an unconventional and/or sustainable way. The use of starting materials less invasive and toxic with respect to the traditional reagents, alternative solvents such as water, ionic liquids or deep eutectic solvents, the exploitation of ultrasound and electrochemistry, increasing the efficiency of the process, are reported. Moreover, representative reaction mechanisms are also discussed" |
| Notes: | "MedlineLanfranco, Alberto Moro, Riccardo Azzi, Emanuele Deagostino, Annamaria Renzi, Polyssena eng Research Support, Non-U.S. Gov't England 2021/08/02 Org Biomol Chem. 2021 Aug 28; 19(32):6926-6957. doi: 10.1039/d1ob01091c. Epub 2021 Aug 1" |
