« Previous Abstract"Predator induced phenotypic plasticity in the pinewoods tree frog, Hyla femoralis: necessary cues and the cost of development"    Next AbstractPreparation of Sourdoughs Fermented with Isolated Lactic Acid Bacteria and Characterization of Their Antifungal Properties »

J Comp Physiol A Neuroethol Sens Neural Behav Physiol

Title:		Responses of round goby (Neogobius melanostomus) olfactory epithelium to steroids released by reproductive males
Author(s):		Laframboise AJ; Zielinski BS;
Address:		"Department of Biological Sciences, University of Windsor, Windsor, ON, Canada"
Journal Title:		J Comp Physiol A Neuroethol Sens Neural Behav Physiol
Year:		2011
Volume:		20110707
Issue:		10
Page Number:		999 - 1008
DOI:		10.1007/s00359-011-0662-5
ISSN/ISBN:		1432-1351 (Electronic) 0340-7594 (Linking)
Abstract:		"The wild perciform teleost Neogobius melanostomus (the round goby) originated from the Ponto-Caspian region and is now a highly successful invasive species in the Laurentian Great Lakes. Males may attract females into their nests for spawning by releasing reproductive pheromones, and it has been previously shown that reproductive males synthesize and release the 5beta-reduced and 3alpha-hydroxyl steroids 3alpha-hydroxy-5beta-androstane-11,17-dione (11-oxo-etiocholanolone; 11-O-ETIO) and 3alpha-hydroxy-5beta-androstane-11,17-dione 3-sulfate (11-oxo-etiocholanolone-3-sulfate; 11-O-ETIO-3-s) and 3alpha,17beta-dihydroxy-5beta-androstan-11-one 17-sulfate. In this study, we investigated properties of these released steroids by recording field potential responses from the olfactory epithelium (electro-olfactogram, EOG). The steroid 3alpha,17beta-dihydroxy-5beta-androstan-11-one 17-sulfate did not elicit olfactory responses while both 11-O-ETIO and 11-O-ETIO-3-s stimulated olfactory field potentials in the round goby, but not in the goldfish. Cross-adaptation analysis demonstrated that round gobies discriminated between11-O-ETIO and 11-O-ETIO-3-s (as well as etiocholanolone, ETIO) at the sensory level. Second messenger cascades depending on both cAMP and IP(3) were inferred for steroids from pharmacological inhibition studies, while the canonical teleost odors taurocholic acid (a bile acid) and L: -alanine (an amino acid) used only cAMP and IP(3), respectively. The round goby presents itself as an excellent species for the study of olfactory function of fish in the wild, given its possible use of these released steroids as pheromones"
Keywords:		Adenine/analogs & derivatives/pharmacology Adenylyl Cyclase Inhibitors Adenylyl Cyclases/metabolism Animals Cyclic AMP/metabolism Dihydrotestosterone/analogs & derivatives/metabolism Enzyme Inhibitors/pharmacology Estrenes/pharmacology Etiocholanolone/ana;
Notes:		"MedlineLaframboise, Alyson J Zielinski, Barbara S eng Comparative Study Research Support, Non-U.S. Gov't Germany 2011/07/08 J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2011 Oct; 197(10):999-1008. doi: 10.1007/s00359-011-0662-5. Epub 2011 Jul 7"