| Title: | Spatial Uncertainty in Modeling Inhalation Exposure to Volatile Organic Compounds in Response to the Application of Consumer Spray Products |
| Author(s): | Jung Y; Kim Y; Seol HS; Lee JH; Kwon JH; |
| Address: | "Division of Environmental Science and Ecological Engineering, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Korea. Program in Public Health, University of California, Irvine, CA 92697, USA. Environment & Safety Research Center, Samsung Electronics Co. Ltd., Samsungjeonja-ro 1, Gyeonggi-do, Hwaseong-si 18448, Korea. EH R&C, Environmental Research Center, 410 Jeongseojin-ro, Seo-gu, Incheon 22689, Korea" |
| Journal Title: | Int J Environ Res Public Health |
| ISSN/ISBN: | 1660-4601 (Electronic) 1661-7827 (Print) 1660-4601 (Linking) |
| Abstract: | "(1) Background: Mathematical exposure modeling of volatile organic compounds (VOCs) in consumer spray products mostly assumes instantaneous mixing in a room. This well-mixed assumption may result in the uncertainty of exposure estimation in terms of spatial resolution. As the inhalation exposure to chemicals from consumer spray products may depend on the spatial heterogeneity, the degree of uncertainty of a well-mixed assumption should be evaluated under specific exposure scenarios. (2) Methods: A room for simulation was divided into eight compartments to simulate inhalation exposure to an ethanol trigger and a propellant product. Real-time measurements of the atmospheric concentration in a room-sized chamber by proton transfer reaction mass spectrometry were compared with mathematical modeling to evaluate the non-homogeneous distribution of chemicals after their application. (3) Results: The well-mixed model overestimated short-term exposure, particularly under the trigger spray scenario. The uncertainty regarding the different chemical proportions in the trigger did not significantly vary in this study. (4) Conclusions: Inhalation exposure to aerosol generating sprays should consider the spatial uncertainty in terms of the estimation of short-term exposure" |
| Keywords: | Aerosols *Inhalation Exposure/analysis Mass Spectrometry Uncertainty *Volatile Organic Compounds inhalation exposure micro environmental modeling proton transfer reaction mass spectrometry (PTR-MS) spray product volatile organic compounds (VOCs); |
| Notes: | "MedlineJung, Yerin Kim, Yoonsub Seol, Hwi-Soo Lee, Jong-Hyeon Kwon, Jung-Hwan eng Research Support, Non-U.S. Gov't Switzerland 2021/06/03 Int J Environ Res Public Health. 2021 May 17; 18(10):5334. doi: 10.3390/ijerph18105334" |
