| Title: | Nematode Pheromones: Structures and Functions |
| Author(s): | Yang B; Wang J; Zheng X; Wang X; |
| Address: | "State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan University, Kunming 650091, China" |
| DOI: | 10.3390/molecules28052409 |
| ISSN/ISBN: | 1420-3049 (Electronic) 1420-3049 (Linking) |
| Abstract: | "Pheromones are chemical signals secreted by one individual that can affect the behaviors of other individuals within the same species. Ascaroside is an evolutionarily conserved family of nematode pheromones that play an integral role in the development, lifespan, propagation, and stress response of nematodes. Their general structure comprises the dideoxysugar ascarylose and fatty-acid-like side chains. Ascarosides can vary structurally and functionally according to the lengths of their side chains and how they are derivatized with different moieties. In this review, we mainly describe the chemical structures of ascarosides and their different effects on the development, mating, and aggregation of nematodes, as well as how they are synthesized and regulated. In addition, we discuss their influences on other species in various aspects. This review provides a reference for the functions and structures of ascarosides and enables their better application" |
| Keywords: | Humans Animals *Caenorhabditis elegans/physiology Pheromones/chemistry Glycolipids/chemistry *Nematoda Reproduction ascarosides functions nematode pheromones structures; |
| Notes: | "MedlineYang, Biyuan Wang, Jie Zheng, Xi Wang, Xin eng 32260029/National Natural Science Foundation of China/ 202101AT070266/Applied Basic Research Foundation of Yunnan Province/ KC-22221839/Postgraduate Research and Innovation Foundation of Yunnan University/ Review Switzerland 2023/03/12 Molecules. 2023 Mar 6; 28(5):2409. doi: 10.3390/molecules28052409" |
